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Browsing by Author "Gandhi, Neel R."

Browsing by Author "Gandhi, Neel R."

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  • Increased Doses Lead to Higher Drug Exposures of Levofloxacin for Treatment of Tuberculosis 
    Peloquin, Charles A.; Phillips, Patrick P. J.; Mitnick, Carole D.; Eisenach, Kathleen; Patientia, Ramonde F.; Lecca, Leonid; Gotuzzo Herencia, José Eduardo; Gandhi, Neel R.; Butler, Donna; Diacon, Andreas H.; Martel, Bruno; Santillan, Juan; Hunt, Kathleen Robergeau; Vargas, Dante; von Groote-Bidlingmaier, Florian; Seas Ramos, Carlos Rafael; Dianis, Nancy; Moreno-Martinez, Antonio; Kaur, Pawandeep; Horsburgh, C. Robert (American Society for Microbiology, 2018)
    Patients with multidrug-resistant tuberculosis in Peru and South Africa were randomized to a weight-banded nominal dose of 11, 14, 17, or 20 mg/kg/day levofloxacin (minimum, 750 mg) in combination with other second-line ...
  • An optimized background regimen design to evaluate the contribution of levofloxacin to multidrug-resistant tuberculosis treatment regimens: study protocol for a randomized controlled trial 
    Bouton, Tara C.; Phillips, Patrick P. J.; Mitnick, Carole D.; Peloquin, Charles A.; Eisenach, Kathleen; Patientia, Ramonde F.; Lecca, Leonid; Gotuzzo Herencia, José Eduardo; Gandhi, Neel R.; Butler, Donna; Diacon, Andreas H.; Martel, Bruno; Santillan, Juan; Hunt, Kathleen Robergeau; Vargas, Dante; von Groote-Bidlingmaier, Florian; Seas Ramos, Carlos Rafael; Dianis, Nancy; Moreno-Martinez, Antonio; Horsburgh, C. Robert (BioMed Central, 2017)
    BACKGROUND: Current guidelines for treatment of multidrug-resistant tuberculosis (MDR-TB) are largely based on expert opinion and observational data. Fluoroquinolones remain an essential part of MDR-TB treatment, but the ...

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