Browsing by Subject "Adaptación Biológica"

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High-Altitude Andean H194R HIF2A Allele Is a Hypomorphic Allele

Jorgensen, Kelsey; Song, Daisheng; Weinstein, Julien; Garcia, Obed A.; Pearson, Laurel N.; Inclán, María; Rivera Chira, Maria Concepcion; León-Velarde, Fabiola; Kiyamu Tsuchiya, Melisa; Brutsaert, Tom D.; Bigham, Abigail W.; Lee, Frank S. (Oxford University Press, 2023)

For over 10,000 years, Andeans have resided at high altitude where the partial pressure of oxygen challenges human survival. Recent studies have provided evidence for positive selection acting in Andeans on the HIF2A (also ...

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