Listar por tema "Histone Deacetylase Inhibitors/adverse effects/pharmacology/therapeutic use"

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Entinostat (SNDX-275) for the treatment of non-small cell lung cancer

Ruiz, Rossana; Raez, Luis E.; Rolfo, Christian (Taylor and Francis, 2015)

INTRODUCTION: Epigenetic aberrations play an important role in lung carcinogenesis. Chromatin deacetylation is a fundamental mechanism of gene silencing. Histone deacetylase (HDAC) inhibitors are an emerging class of ...