Listar por tema "antimalarial agent"

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  • Factors predictive of serious infections over time in systemic lupus erythematosus patients: data from a multi-ethnic, multi-national, Latin American lupus cohort 
    Pimentel Quiroz, Víctor Roman; Ugarte Gil, Manuel Francisco; Harvey, G. B.; Wojdyla, D.; Pons-Estel, G. J.; Quintana, R.; Esposto, A.; Garcia, M. A.; Catoggio, L. J.; Cardiel, M. H.; Barile, L. A.; Amigo, M.-C.; Sato, E. I.; Bonfa, E.; Borba, E.; Lavras Costallat, L. T.; Neira, O. J.; Massardo, L.; Guibert-Toledano, M.; Chacon-Diaz, R.; Alarcón, Graciela S.; Pons-Estel, B. A. (SAGE Publications, 2019)
    AIM: The aim of this study was to identify factors predictive of serious infections over time in patients with systemic lupus erythematosus (SLE). METHODS: A multi-ethnic, multi-national Latin American SLE cohort was ...
  • The history of 20th century malaria control in Peru 
    Griffing, Sean M.; Gamboa Vilela, Dionicia Baziliza; Udhayakumar, Venkatachalam (BioMed Central, 2013)
    Malaria has been part of Peruvian life since at least the 1500s. While Peru gave the world quinine, one of the first treatments for malaria, its history is pockmarked with endemic malaria and occasional epidemics. In this ...
  • Molecular epidemiology of plasmodium falciparum malaria outbreak, Tumbes, Peru, 2010–2012 
    Baldeviano, G.C.; Akinyi Okoth, S.; Arrospide, N.; Gonzalez, R.V.; Sánchez, J.F.; Macedo, S.; Conde, S.; Tapia, L.L.; Salas, C.; Gamboa Vilela, Dionicia Baziliza; Herrera, Y.; Edgel, K.A.; Udhayakumar, V.; Lescano Guevara, Andres Guillermo (Centers for Disease Control and Prevention, 2015)
    During 2010–2012, an outbreak of 210 cases of malaria occurred in Tumbes, in the northern coast of Peru, where no Plasmodium falciparum malaria case had been reported since 2006. To identify the source of the parasite ...
  • New findings on Simalikalactone D, an antimalarial compound from Quassia amara L. (Simaroubaceae) 
    Bertani, S.; Houël, E.; Jullian, V.; Bourdy, G.; Valentin, A.; Stien, D.; Deharo, E. (Elsevier, 2012)
    Quassia amara L. (Simaroubaceae) is a species widely used as tonic and is claimed to be an efficient antimalarial all over the Northern part of the Amazon basin. Quassinoid compound Simalikalactone D (SkD) has been shown ...
  • Organ damage in systemic lupus erythematosus 
    González, Luis Alonso; Santamaría-Alza, Yeison; Alarcón, Graciela S. (Elsevier, 2021)
    Damage reflects the irreversible changes that occur in systemic lupus erythematosus (SLE) patients as a consequence of the disease, its treatment or comorbidities. The pattern of damage increases in a steady linear fashion ...
  • Serum uric acid is associated with damage in patients with systemic lupus erythematosus 
    Elera-Fitzcarrald, C.; Reátegui-Sokolova, C.; Gamboa-Cardenas, R.V.; Medina, M.; Zevallos, F.; Pimentel Quiroz, Víctor Roman; Cucho-Venegas, J.M.; Alfaro-Lozano, J.; Rodriguez-Bellido, Z.; Pastor-Asurza, C.A.; Perich-Campos, R.A.; Alarcón, Graciela S.; Ugarte Gil, Manuel Francisco (BMJ Publishing Group, 2020)
    Introduction: Serum uric acid levels have been reported as predictors of cardiovascular, pulmonary, neurological and renal morbidity in patients with SLE. However, their role in cumulative global damage in these patients ...
  • Single-dose tafenoquine to prevent relapse of plasmodium vivax malaria 
    Lacerda, M.V.G.; Llanos Cuentas, Elmer Alejandro; Krudsood, S.; Lon, C.; Saunders, D.L.; Mohammed, R.; Yilma, D.; Pereira, D.B.; Espino, F.E.J.; Mia, R.Z.; Chuquiyauri, R.; Val, F.; Casapía, M.; Monteiro, W.M.; Brito, M.A.M.; Costa, M.R.F.; Buathong, N.; Noedl, H.; Diro, E.; Getie, S.; Wubie, K.M.; Abdissa, A.; Zeynudin, A.; Abebe, C.; Tada, M.S.; Brand, F.; Beck, H.-P.; Angus, B.; Duparc, S.; Kleim, J.-P.; Kellam, L.M.; Rousell, V.M.; Jones, S.W.; Hardaker, E.; Mohamed, K.; Clover, D.D.; Fletcher, K.; Breton, J.J.; Ugwuegbulam, C.O.; Green, J.A.; Koh, G.C.K.W. (Massachusetts Medical Society, 2019)
    BACKGROUND: Treatment of Plasmodium vivax malaria requires the clearing of asexual parasites, but relapse can be prevented only if dormant hypnozoites are cleared from the liver (a treatment termed "radical cure"). Tafenoquine ...
  • Systemic lupus erythematosus: A therapeutic challenge for the XXI century 
    Ugarte Gil, Manuel Francisco; Alarcón, Graciela S. (Springer, 2014)
    Despite significant advances in our understanding of the pathogenesis of systemic lupus erythematosus (SLE), there are only a few drugs approved by the regulatory agencies across the world for the treatment of these patients; ...
  • Tafenoquine versus primaquine to prevent relapse of plasmodium vivax malaria 
    Llanos Cuentas, Elmer Alejandro; Lacerda, M.V.G.; Hien, T.T.; Vélez, I.D.; Namaik-Larp, C.; Chu, C.S.; Villegas, M.F.; Val, F.; Monteiro, W.M.; Brito, M.A.M.; Costa, M.R.F.; Chuquiyauri, R.; Casapía, M.; Nguyen, C.H.; Aruachan, S.; Papwijitsil, R.; Nosten, F.H.; Bancone, G.; Angus, B.; Duparc, S.; Craig, G.; Rousell, V.M.; Jones, S.W.; Hardaker, E.; Clover, D.D.; Kendall, L.; Mohamed, K.; Koh, G.C.K.W.; Wilches, V.M.; Breton, J.J.; Green, J.A. (Massachusetts Medical Society, 2019)
    BACKGROUND: Tafenoquine, a single-dose therapy for Plasmodium vivax malaria, has been associated with relapse prevention through the clearance of P. vivax parasitemia and hypnozoites, termed "radical cure." METHODS: We ...

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