Listar por tema "antitubercular agents"

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Increased Doses Lead to Higher Drug Exposures of Levofloxacin for Treatment of Tuberculosis

Peloquin, Charles A.; Phillips, Patrick P. J.; Mitnick, Carole D.; Eisenach, Kathleen; Patientia, Ramonde F.; Lecca, Leonid; Gotuzzo Herencia, José Eduardo; Gandhi, Neel R.; Butler, Donna; Diacon, Andreas H.; Martel, Bruno; Santillan, Juan; Hunt, Kathleen Robergeau; Vargas, Dante; von Groote-Bidlingmaier, Florian; Seas Ramos, Carlos Rafael; Dianis, Nancy; Moreno-Martinez, Antonio; Kaur, Pawandeep; Horsburgh, C. Robert (American Society for Microbiology, 2018)

Patients with multidrug-resistant tuberculosis in Peru and South Africa were randomized to a weight-banded nominal dose of 11, 14, 17, or 20 mg/kg/day levofloxacin (minimum, 750 mg) in combination with other second-line ...