Listar por tema "human experiment"

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  • The ARMADILLO text message intervention to improve the sexual and reproductive health knowledge of adolescents in Peru: Results of a randomized controlled trial 
    Perez-Lu, Jose E.; Guerrero, Fiorella; Cárcamo Cavagnaro, César Paul Eugenio; Alburqueque, Monica; Chiappe Gutierrez, Marina Angelica; Hindin, Michelle J.; Habib, Ndema; Say, Lale; Gonsalves, Lianne; Bayer, Angela M. (Public Library of Science, 2022)
    Background The ARMADILLO Study determined whether adolescents able to access SRH information on-demand via SMS were better able to reject contraception-related myths and misconceptions as compared with adolescents receiving ...
  • Asymmetric dimethylarginine at sea level is a predictive marker of hypoxic pulmonary arterial hypertension at high altitude 
    Siques, Patricia; Brito, Julio; Schwedhelm, Edzard; Pena, Eduardo; León-Velarde, Fabiola; De La Cruz, Juan Jose; Boeger, Rainer H.; Hannemann, Juliane (Frontiers Media, 2019)
    Background: Prolonged exposure to altitude-associated chronic hypoxia (CH) may cause high-altitude pulmonary hypertension (HAPH). Chronic intermittent hypobaric hypoxia (CIH) occurs in individuals who commute between sea ...
  • Building a Data Platform for Cross-Country Urban Health Studies: the SALURBAL Study 
    Quistberg, D. Alex; Diez Roux, Ana V.; Bilal, Usama; Moore, Kari; Ortigoza, Ana; Rodriguez, Daniel A.; Sarmiento, Olga L.; Frenz, Patricia; Friche, Amelia Augusta; Caiaffa, Waleska Teixeira; Vives, Alejandra; Miranda, J. Jaime; SALURBAL Group (Springer, 2018)
    Studies examining urban health and the environment must ensure comparability of measures across cities and countries. We describe a data platform and process that integrates health outcomes together with physical and social ...
  • Cognitive function and mood at high altitude following acclimatization and use of supplemental oxygen and adaptive servoventilation sleep treatments. 
    Heinrich, Erica C.; Djokic, Matea A.; Gilbertson, Dillon; DeYoung, Pamela N.; Bosompra, Naa-Oye; Wu, Lu; Anza-Ramirez, Cecilia; Orr, Jeremy E.; Powell, Frank L.; Malhotra, Atul; Simonson, Tatum S. (Public Library of Science, 2019)
    Impairments in cognitive function, mood, and sleep quality occur following ascent to high altitude. Low oxygen (hypoxia) and poor sleep quality are both linked to impaired cognitive performance, but their independent ...
  • A community-based approach to integrating socio, cultural and environmental contexts in the development of a food database for indigenous and rural populations: The case of the batwa and bakiga in south-western Uganda 
    Scarpa, G.; Berrang-Ford, L.; Twesigomwe, S.; Kakwangire, P.; Peters, R.; Zavaleta Cortijo, Claudia Carol; Patterson, K.; Namanya, D.B.; Lwasa, S.; Nowembabazi, E.; Kesande, C.; Harris-Fry, H.; Cade, J.E. (MDPI, 2021)
    Comprehensive food lists and databases are a critical input for programs aiming to alleviate undernutrition. However, standard methods for developing them may produce databases that are irrelevant for marginalised groups ...
  • Conceptual framework of mentoring in low- and middle-income countries to advance global health 
    Prasad, S.; Sopdie, E.; Meya, D.; Kalbarczyk, A.; Garcia Funegra, Patricia Jannet (American Society of Tropical Medicine and Hygiene, 2019)
    Although mentoring is not a common practice in low- and middle-income countries (LMICs), there is a strong need for it. Conceptual frameworks provide the structure to design, study, and problem-solve complex phenomena. ...
  • A cross-sectional study of differences in 6-min walk distance in healthy adults residing at high altitude versus sea level 
    Caffrey, Deirdre; Miranda, J. Jaime; Gilman, Robert Hugh; Davila-Roman, Victor G.; Cabrera, Lilia; Dowling, Russell; Stewart, Talia; Bernabé Ortiz, Antonio; Wise, Robert; León-Velarde, Fabiola; Checkley, William; CRONICAS Cohort (BioMed Central, 2014)
    Background: We sought to determine if adult residents living at high altitude have developed sufficient adaptation to a hypoxic environment to match the functional capacity of a similar population at sea level. To test ...
  • The development of an online risk calculator for the prediction of future syphilis among a high-risk cohort of men who have sex with men and transgender women in Lima, Peru 
    Allan-Blitz, Lao-Tzu; Konda, Kelika A.; Vargas Rivera, Silver Keith; Wang, Xiaoyan; Segura, Eddy R.; Fazio, Boris M.; Calvo, Gino M.; Caceres Palacios, Carlos Fernando; Klausner, Jeffrey D. (CSIRO Publishing, 2018)
    Background: Syphilis incidence worldwide has rebounded since 2000, particularly among men who have sex with men (MSM). A predictive model for syphilis infection may inform prevention counselling and use of chemoprophylaxis. ...
  • Facial asymmetry and genetic ancestry in Latin American admixed populations 
    Quinto-Sánchez, Mirsha; Adhikari, K.; Acuña-Alonzo, V.; Cintas, C.; Silva De Cerqueira, C.C.; Ramallo, V.; Castillo, L.; Farrera, A.; Jaramillo, C.; Arias, W.; Fuentes, M.; Everardo, P.; De Avila, F.; Gomez-Valdés, J.; Hünemeier, T.; Gibbon, S.; Gallo López-Aliaga, Carla Maria; Poletti, Giovanni; Rosique, J.; Bortolini, M.C.; Canizales-Quinteros, S.; Rothhammer, F.; Bedoya, G.; Ruiz-Linares, A.; González-José, R. (Wiley, 2015)
    Fluctuating and directional asymmetry are aspects of morphological variation widely used to infer environmental and genetic factors affecting facial phenotypes. However, the genetic basis and environmental determinants of ...
  • Genetic components of human pain sensitivity: A protocol for a genome-wide association study of experimental pain in healthy volunteers 
    Schmid, Annina B.; Adhikari, Kaustubh; Ramirez-Aristeguieta, Luis Miguel; Chacon-Duque, Juan-Camilo; Poletti, Giovanni; Gallo López-Aliaga, Carla Maria; Rothhammer, Francisco; Bedoya, Gabriel; Ruiz-Linares, Andres; Bennett, David L. (BMJ Publishing Group, 2019)
    INTRODUCTION: Pain constitutes a major component of the global burden of diseases. Recent studies suggest a strong genetic contribution to pain susceptibility and severity. Whereas most of the available evidence relies on ...
  • A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia 
    Adhikari, K.; Mendoza-Revilla, J.; Sohail, A.; Fuentes-Guajardo, M.; Lampert, J.; Chacón-Duque, J.C.; Hurtado, M.; Villegas, V.; Granja, V.; Acuña-Alonzo, V.; Jaramillo, C.; Arias, W.; Lozano, R.B.; Everardo, P.; Gómez-Valdés, J.; Villamil-Ramírez, H.; Silva de Cerqueira, C.C.; Hunemeier, T.; Ramallo, V.; Schuler-Faccini, L.; Salzano, F.M.; Gonzalez-José, R.; Bortolini, M.-C.; Canizales-Quinteros, S.; Gallo López-Aliaga, Carla Maria; Poletti, G.; Bedoya, G.; Rothhammer, F.; Tobin, D.J.; Fumagalli, M.; Balding, D.; Ruiz-Linares, A. (Springer Nature, 2019)
    We report a genome-wide association scan in >6,000 Latin Americans for pigmentation of skin and eyes. We found eighteen signals of association at twelve genomic regions. These include one novel locus for skin pigmentation ...
  • Impact of an Andean breakfast on biochemistry and immunochemistry laboratory tests: an evaluation on behalf COLABIOCLI WG-PRE-LATAM. 
    Bajaña, W.; Aranda, E.; Arredondo, M.E.; Brennan-Bourdon, L.M.; Campelo, M.D.; Espinoza, E.; Flores, S.; Ochoa, P.; Vega, V.; Varela, B.; Lima-Oliveira, G. (Croatian Society of Medical Biochemistry and Laboratory Medicine, 2019)
    Introduction: In Andean countries, specifically in Ecuador, a food transition in the population has been observed because of economic growth. The Working Group for Preanalytical Phase in Latin America (WG-PRE-LATAM) of the ...
  • Implications of the admixture process in skin color molecular assessment 
    Cerqueira, Caio Cesar Silva de; Hünemeier, Tábita; Gomez-Valdés, Jorge; Ramallo, Virgínia; Volasko-Krause, Carla Daiana; Barbosa, Ana Angélica Leal; Vargas-Pinilla, Pedro; Dornelles, Rodrigo Ciconet; Longo, Danaê; Rothhammer, Francisco; Bedoya, Gabriel; Canizales-Quinteros, Samuel; Acuña-Alonzo, Victor; Gallo López-Aliaga, Carla Maria; Poletti, Giovanni; González-José, Rolando; Salzano, Francisco Mauro; Callegari-Jacques, Sídia Maria; Schuler-Faccini, Lavínia; Ruiz-Linares, Andrés; Cátira Bortolini, Maria (Public Library of Science, 2014)
    The understanding of the complex genotype-phenotype architecture of human pigmentation has clear implications for the evolutionary history of humans, as well as for medical and forensic practices. Although dozens of genes ...
  • Intragenerational social mobility and self-rated oral health in the british cohort study 
    Mohd Khairuddin, A.N.; Bernabé, E.; Delgado-Angulo, E.K. (Springer, 2021)
    Background: Most studies on social mobility and oral health have focused on movement between generations (intergenerational mobility) rather than movement within an individual’s own lifetime (intragenerational mobility). ...
  • Kaniuwatewara (when we get sick): understanding health-seeking behaviours among the Shawi of the Peruvian Amazon 
    Bussalleu Cavero, Alejandra Estefania; Pizango, P.; King, N.; Ford, J.; Team, I.H.A.C.C.R.; Harper, S.L. (BioMed Central, 2021)
    Background: Detailed qualitative information regarding Indigenous populations’ health-seeking behaviours within Peru’s plural healthcare system is lacking. Such context-specific information is prerequisite to developing ...
  • Measuring the quality of sexuality education implementation at the school level in low- and middle-income countries 
    Keogh, S.C.; Stillman, M.; Leong, E.; Awusabo-Asare, K.; Sidze, E.; Monzón, A.S.; Motta, A. (Taylor and Francis, 2019)
    Comprehensive sexuality education (CSE) is a key component of efforts to improve sexual and reproductive outcomes for young people. While many governments have established policies and curricula for CSE, there are no ...
  • Origins, admixture dynamics and homogenization of the African gene pool in the Americas 
    Gouveia, Mateus H.; Borda, Victor; Leal, Thiago P.; Moreira, Rennan G.; Bergen, Andrew W.; Kehdy, Fernanda S. G.; Alvim, Isabela; Aquino, Marla M.; Araujo, Gilderlanio S.; Araujo, Nathalia M.; Furlan, Vinicius; Liboredo, Raquel; Machado, Moara; Magalhaes, Wagner C. S.; Michelin, Lucas A.; Rodrigues, Maíra R.; Rodrigues-Soares, Fernanda; Sant Anna, Hanaisa P.; Santolalla Robles, Meddly Leslye; Scliar, Marília O.; Soares-Souza, Giordano; Zamudio, Roxana; Zolini, Camila; Bortolini, Maria Catira; Dean, Michael; Gilman, Robert Hugh; Guio, Heinner; Rocha, Jorge; Pereira, Alexandre C.; Barreto, Mauricio L.; Horta, Bernardo L.; Lima-Costa, Maria F.; Mbulaiteye, Sam M.; Chanock, Stephen J.; Tishkoff, Sarah A.; Yeager, Meredith; Tarazona-Santos, Eduardo (Oxford University Press, 2020)
    The Transatlantic Slave Trade transported more than 9 million Africans to the Americas between the early 16th and the mid-19th centuries. We performed a genome-wide analysis using 6,267 individuals from 25 populations to ...
  • The overlooked significance of plasma volume for successful adaptation to high altitude in Sherpa and Andean natives 
    Stembridge, Mike; Williams, Alexandra M.; Gasho, Christopher; Dawkins, Tony G.; Drane, Aimee; Villafuerte, Francisco C.; Levine, Benjamin D.; Shave, Rob; Ainslie, Philip N. (National Academy of Sciences, 2019)
    In contrast to Andean natives, high-altitude Tibetans present with a lower hemoglobin concentration that correlates with reproductive success and exercise capacity. Decades of physiological and genomic research have assumed ...
  • Physical activity and sedentary behavior patterns and sociodemographic correlates in 116,982 adults from six South American countries: the South American physical activity and sedentary behavior network (SAPASEN). 
    Werneck, Andre O.; Baldew, Se-Sergio; Miranda, J. Jaime; Diaz Arnesto, Oscar; Stubbs, Brendon; Silva, Danilo R. (BioMed Central, 2019)
    BACKGROUND: Physical inactivity and sedentary behavior are major concerns for public health. Although global initiatives have been successful in monitoring physical activity (PA) worldwide, there is no systematic action ...
  • Physical activity, physical condition and quality of life in schoolchildren 
    Uribe, S.C.; Arista-Huaco, M.J.; Encalada-Díaz, I.A.; Isla-Alcoser, S.D. (Research Group on Physical Activity and Sports Sciences (GICAFD), 2021)
    The study analyses the physical condition and quality of life on the physical activity of schoolchildren in a Peruvian educational institution, applying a non-probability and convenience sampling, to 168 first-year high ...

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