Universidad Peruana Cayetano Heredia

Anti-triatomine saliva immunoassays for the evaluation of impregnated netting trials against Chagas disease transmission

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dc.contributor.author Schwarz, A.
dc.contributor.author Juarez, J.A.
dc.contributor.author Richards, J.
dc.contributor.author Rath, B.
dc.contributor.author Machaca, V.Q.
dc.contributor.author Castro, Y.E.
dc.contributor.author Málaga, E.S.
dc.contributor.author Levy, K.
dc.contributor.author Gilman, Robert Hugh
dc.contributor.author Bern, C.
dc.contributor.author Verastegui Pimentel, Manuela Renee
dc.contributor.author Levy, M.Z.
dc.date.accessioned 2022-01-18T19:26:46Z
dc.date.available 2022-01-18T19:26:46Z
dc.date.issued 2011
dc.identifier.uri https://hdl.handle.net/20.500.12866/10863
dc.description.abstract Insecticide-impregnated nets can kill triatomine bugs, but it remains unclear whether they can protect against Chagas disease transmission. In a field trial in Quequeña, Peru, sentinel guinea pigs placed in intervention enclosures covered by deltamethrin-treated nets showed significantly lower antibody responses to saliva of Triatoma infestans compared with animals placed in pre-existing control enclosures. Our results strongly suggest that insecticide-treated nets prevent triatomine bites and can thereby protect against infection with Trypanosoma cruzi. Anti-salivary immunoassays are powerful new tools to evaluate intervention strategies against Chagas disease. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries International Journal for Parasitology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Male en_US
dc.subject Peru en_US
dc.subject Controlled Study en_US
dc.subject Animal Experiment en_US
dc.subject Disease Transmission en_US
dc.subject Insecticide-Treated Bednets en_US
dc.subject Infection Prevention en_US
dc.subject Chagas Disease en_US
dc.subject Guinea Pigs en_US
dc.subject Trypanosoma Cruzi en_US
dc.subject Antibody Response en_US
dc.subject Animalia en_US
dc.subject Immunoassay en_US
dc.subject Cavia en_US
dc.subject Parasitology en_US
dc.subject Antibody en_US
dc.subject Deltamethrin en_US
dc.subject Insect Control en_US
dc.subject Triatoma en_US
dc.subject Triatoma Infestans en_US
dc.subject Antibody Response en_US
dc.subject Experimental Guinea Pig en_US
dc.subject Impregnated Net en_US
dc.subject Insect Bites And Stings en_US
dc.subject Saliva Analysis en_US
dc.subject Sentinel Guinea Pig en_US
dc.title Anti-triatomine saliva immunoassays for the evaluation of impregnated netting trials against Chagas disease transmission en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.ijpara.2011.02.001
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.07
dc.relation.issn 1879-0135


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