Universidad Peruana Cayetano Heredia

Balamuthia mandrillaris infection of the skin and central nervous system: An emerging disease of concern to many specialties in medicine

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dc.contributor.author Bravo Puccio, Francisco Gerardo
dc.contributor.author Alvarez, P.J.
dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.date.accessioned 2022-01-18T19:26:52Z
dc.date.available 2022-01-18T19:26:52Z
dc.date.issued 2011
dc.identifier.uri https://hdl.handle.net/20.500.12866/10962
dc.description.abstract Purpose of Review: Balamuthia mandrillaris infection of the skin and central nervous system has been increasingly reported in the last decade, making this entity a genuine emerging disease. The ability of the clinician in recognizing the skin lesion early in the course of the disease may lead to a successful therapeutic intervention in an otherwise fatal disease. RECENT FINDINGS: In the past years, advances have been made regarding knowledge about the ubiquity of the ameba in the environment, its worldwide distribution (with higher prevalence in South America), the patients at risk (particularly those of Hispanic origin), the diagnostic methods (including those based on molecular biology) and the different therapeutic strategies that have resulted in survival of patients. A recent report dealing with organ transplant transmission of this infection has made it a subject of interest in transplant medicine. SUMMARY: The present review will allow readers from different fields (clinician, dermatologist, neurologist, infectious disease and transplant specialist) to become familiar with the clinical aspect of the disease, including diagnosis and therapy. en_US
dc.language.iso eng
dc.publisher Wolters Kluwer Health
dc.relation.ispartofseries Current Opinion in Infectious Diseases
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Humans en_US
dc.subject Polymerase Chain Reaction en_US
dc.subject Fever en_US
dc.subject Headache en_US
dc.subject Mortality en_US
dc.subject Pyrrole Derivative en_US
dc.subject Flow Cytometry en_US
dc.subject Skin Biopsy en_US
dc.subject Albendazole en_US
dc.subject Serology en_US
dc.subject Skin Defect en_US
dc.subject Enzyme Linked Immunosorbent Assay en_US
dc.subject Azithromycin en_US
dc.subject Cotrimoxazole en_US
dc.subject Immunohistochemistry en_US
dc.subject Fluconazole en_US
dc.subject Metronidazole en_US
dc.subject Paromomycin en_US
dc.subject Amphotericin B en_US
dc.subject Brain Necrosis en_US
dc.subject Antiprotozoal Agents en_US
dc.subject Molecular Biology en_US
dc.subject Macrolide en_US
dc.subject Intracranial Hypertension en_US
dc.subject Amebiasis en_US
dc.subject Artesunate en_US
dc.subject Balamuthia Infection en_US
dc.subject Balamuthia Mandrillaris en_US
dc.subject Clarithromycin en_US
dc.subject Encephalitis en_US
dc.subject Inflammatory Infiltrate en_US
dc.subject Itraconazole en_US
dc.subject Miltefosine en_US
dc.subject Skin Diseases Parasitic en_US
dc.subject Trophozoite en_US
dc.subject Brain Hemorrhage en_US
dc.subject Flucytosine en_US
dc.subject Photophobia en_US
dc.subject Pleocytosis en_US
dc.subject Sulfadiazine en_US
dc.subject Thioridazine en_US
dc.subject Organ Transplantation en_US
dc.subject Immunocompromised Host en_US
dc.subject Seizure en_US
dc.subject Ameba en_US
dc.subject Amoeba en_US
dc.subject Anisocoria en_US
dc.subject Balamuthia en_US
dc.subject Central Nervous System Protozoal Infections en_US
dc.subject Cerebrospinal Fluid Cytology en_US
dc.subject Coma en_US
dc.subject Communicable Diseases Emerging en_US
dc.subject Consciousness Level en_US
dc.subject Face Injury en_US
dc.subject Granulomatous Inflammation en_US
dc.subject Immunofluorescence Test en_US
dc.subject Isethionic Acid en_US
dc.subject Lethargy en_US
dc.subject Motor Dysfunction en_US
dc.subject Pentamidine en_US
dc.subject Sensory Dysfunction en_US
dc.subject Skin Lesion en_US
dc.title Balamuthia mandrillaris infection of the skin and central nervous system: An emerging disease of concern to many specialties in medicine en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1097/QCO.0b013e3283428d1e
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08
dc.relation.issn 1473-6527


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