Universidad Peruana Cayetano Heredia

Relationship between care model and disease activity states and health-related quality of life in systemic lupus erythematosus patients

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dc.contributor.author Perea-Seoane, Luciana
dc.contributor.author Agapito-Vera, Estefania
dc.contributor.author Gamboa-Cardenas, Rocío V.
dc.contributor.author Guzmán-Sánchez, Geny
dc.contributor.author Pimentel Quiroz, Víctor Roman
dc.contributor.author Reategui-Sokolova, Cristina
dc.contributor.author Medina, Mariela
dc.contributor.author Elera-Fitzcarrald, Claudia
dc.contributor.author Noriega, Erika
dc.contributor.author Rodriguez-Bellido, Zoila
dc.contributor.author Pastor-Asurza, Cesar
dc.contributor.author Perich-Campos, Risto
dc.contributor.author Alarcón, Graciela S.
dc.contributor.author Ugarte Gil, Manuel Francisco
dc.date.accessioned 2022-02-17T19:23:13Z
dc.date.available 2022-02-17T19:23:13Z
dc.date.issued 2022
dc.identifier.uri https://hdl.handle.net/20.500.12866/11388
dc.description.abstract Objective: To assess whether the care model (comprehensive vs regular) has any impact on the clinical outcomes of systemic lupus erythematosus patients. Methods: Between August 2019 and January 2020, we evaluated SLE patients being cared for at two Peruvian hospitals to define the impact of care model on disease activity state and health-related quality of life (HRQoL). Disease activity was ascertained with the SLEDAI-2K and the Physician Global Assessment (PGA) which allows to define Lupus Low Disease Activity State (LLDAS) and Remission. HRQoL was measured with the LupusQoL. The association between care model and disease activity (Remission and LLDAS) state was examined using a binary logistic regression model. The association with HRQoL was examined with a linear regression model. All multivariable analyses were adjusted for possible confounders. Results: 266 SLE patients were included, 227 from the comprehensive care model and 39 from the regular care model. The regular care model was associated with a lower probability of achieving remission (OR 0.381; CI: 95% 0.163–0.887) and LLDAS (OR 0.363; CI: 95% 0.157–0.835). Regular care was associated with a better HRQoL in two domains (pain and emotional health). We found no association between the care model and the other HRQoL domains. Conclusion: A comprehensive care model was associated with the probability of achieving remission and LLDAS but had no apparent impact on the patients’ HRQoL. en_US
dc.language.iso eng
dc.publisher SAGE Publications
dc.relation.ispartofseries Lupus
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Systemic lupus erythematosus en_US
dc.subject Remission en_US
dc.subject Care model en_US
dc.subject Damage en_US
dc.subject Health-related quality of care en_US
dc.subject Low lupus disease activity state en_US
dc.title Relationship between care model and disease activity states and health-related quality of life in systemic lupus erythematosus patients en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1177/09612033211063798
dc.relation.issn 1477-0962


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