Universidad Peruana Cayetano Heredia

Indoor air pollution concentrations and cardiometabolic health across four diverse settings in Peru: a cross-sectional study

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dc.contributor.author Kephart, Josiah L.
dc.contributor.author Fandiño-Del-Rio, Magdalena
dc.contributor.author Koehler, Kirsten
dc.contributor.author Bernabé Ortiz, Antonio
dc.contributor.author Miranda, J. Jaime
dc.contributor.author Gilman, Robert Hugh
dc.contributor.author Checkley, William
dc.date.accessioned 2020-07-14T00:02:29Z
dc.date.available 2020-07-14T00:02:29Z
dc.date.issued 2020
dc.identifier.uri https://hdl.handle.net/20.500.12866/8315
dc.description.abstract BACKGROUND: Indoor air pollution is an important risk factor for health in low- and middle-income countries. METHODS: We measured indoor fine particulate matter (PM2.5) and carbon monoxide (CO) concentrations in 617 houses across four settings with varying urbanisation, altitude, and biomass cookstove use in Peru, between 2010 and 2016. We assessed the associations between indoor pollutant concentrations and blood pressure (BP), exhaled carbon monoxide (eCO), C-reactive protein (CRP), and haemoglobin A1c (HbA1c) using multivariable linear regression among all participants and stratifying by use of biomass cookstoves. RESULTS: We found high concentrations of indoor PM2.5 across all four settings (geometric mean ± geometric standard deviation of PM2.5 daily average in μg/m3): Lima 41.1 ± 1.3, Tumbes 35.8 ± 1.4, urban Puno 14.1 ± 1.7, and rural Puno 58.8 ± 3.1. High indoor CO concentrations were common in rural households (geometric mean ± geometric standard deviation of CO daily average in ppm): rural Puno 4.9 ± 4.3. Higher indoor PM2.5 was associated with having a higher systolic BP (1.51 mmHg per interquartile range (IQR) increase, 95% CI 0.16 to 2.86), a higher diastolic BP (1.39 mmHg higher DBP per IQR increase, 95% CI 0.52 to 2.25), and a higher eCO (2.05 ppm higher per IQR increase, 95% CI 0.52 to 3.57). When stratifying by biomass cookstove use, our results were consistent with effect measure modification in the association between PM2.5 and eCO: among biomass users eCO was 0.20 ppm higher per IQR increase in PM2.5 (95% CI - 2.05 to 2.46), and among non-biomass users eCO was 5.00 ppm higher per IQR increase in PM2.5 (95% CI 1.58 to 8.41). We did not find associations between indoor air concentrations and CRP or HbA1c outcomes. CONCLUSIONS: Excessive indoor concentrations of PM2.5 are widespread in homes across varying levels of urbanisation, altitude, and biomass cookstove use in Peru and are associated with worse BP and higher eCO. en_US
dc.language.iso eng
dc.publisher BioMed Central
dc.relation.ispartofseries Environmental Health: A Global Access Science Source
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Peru en_US
dc.subject Latin America en_US
dc.subject Air pollution epidemiology en_US
dc.subject Blood pressure en_US
dc.subject C-reactive protein en_US
dc.subject Carbon monoxide en_US
dc.subject Exhaled carbon monoxide en_US
dc.subject Haemoglobin A1c en_US
dc.subject Indoor air pollution en_US
dc.subject Particulate matter en_US
dc.title Indoor air pollution concentrations and cardiometabolic health across four diverse settings in Peru: a cross-sectional study en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1186/s12940-020-00612-y
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 1476-069X


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