Listar por tema "Leishmaniasis"

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  • Accurate and rapid species typing from cutaneous and mucocutaneous leishmaniasis lesions of the New World 
    Fraga, J.; Veland, N.; Montalvo, A.M.; Praet, N.; Boggild, A.K.; Valencia, B.M.; Arévalo Zelada, Jorge Luis; Llanos Cuentas, Elmer Alejandro; Dujardin, J.-C.; Van der Auwera, G. (Elsevier, 2012)
    The heat-shock protein 70 gene (hsp70) has been exploited for Leishmania species identification in the Old and New World, using polymerase chain reaction (PCR) followed by restriction fragment length polymorphism analysis. ...
  • Activity-guided isolation of antileishmanial compounds from Piper hispidum 
    Ruiz, C.; Haddad, M.; Alban, J.; Bourdy, G.; Reategui, R.; Castillo Pareja, Denis Helan; Sauvain, Michel Henri Auguste; Deharo, E.; Estevez, Y.; Arévalo Zelada, Jorge Luis; Rojas, R. (Elsevier, 2011)
    The bioassay-guided purification of the ethanolic extract from the leaves of Piper hispidum led to the isolation of one new amide, N-2-(3′,4′, 5′-trimethoxyphenyl)ethyl-2-hydroxybenzamide (1) as well as two known chalcones ...
  • Antileishmanial sesquiterpene lactones from Pseudelephantopus spicatus, a traditional remedy from the Chayahuita Amerindians (Peru). Part III 
    Odonne, G.; Herbette, G.; Eparvier, V.; Bourdy, G.; Rojas, R.; Sauvain, Michel Henri Auguste; Stien, D. (Elsevier, 2011)
    Ethnopharmacological relevance: The study of traditional remedies used by the Chayahuita, an ethnic group from the Peruvian Amazonia, has prompted us to investigate in detail the ethanolic extract of Pseudelephantopus ...
  • Calcified bodies in new world cutaneous leishmaniasis 
    Alvarez, P.; Salinas, C.; Bravo Puccio, Francisco Gerardo (Wolters Kluwer Health, 2011)
    We report a case of a 9-year-old boy who presented with 2 lesions that were compatible clinically with cutaneous leishmaniasis of the New World. A skin biopsy showed tuberculoid granulomas with rounded calcified bodies. ...
  • Clinical pleiomorphism in human leishmaniases, with special mention of asymptomatic infection 
    Bañuls, A.L.; Bastien, P.; Pomares, C.; Arévalo Zelada, Jorge Luis; Fisa, R.; Hide, M. (Elsevier, 2011)
    This review gives an update of current knowledge on the clinical pleiomorphism of Leishmania, with a special emphasis on the case of asymptomatic carriage. The first part describes the numerous unusual expressions of the ...
  • Diversity, distribution and natural Leishmania infection of sand flies from communities along the Interoceanic Highway in the Southeastern Peruvian Amazon 
    Valdivia, Hugo O.; Zorrilla, Victor O.; Espada, Liz J.; Perez, Jocelyn G.; Razuri, Hugo R.; Vera, Hubert; Fernandez, Roberto; Tong, Carlos; Ghersi, Bruno M.; Vasquez, Gissella M.; Burrus, Roxanne G.; Lescano Guevara, Andres Guillermo; Montgomery, Joel M. (Public Library of Science, 2021)
    The Peruvian-Brazilian border is a highly endemic tegumentary leishmaniasis region in South America. The interoceanic highway is a commercial route that connects Peru and Brazil through Madre de Dios and has raised concerns ...
  • Evaluation of a diagnostic device, CL Detect rapid test for the diagnosis of new world cutaneous leishmaniasis in Peru 
    Grogl, Max; Joya, Christie A.; Saenz, Maria; Quispe, Ana; Rosales, Luis Angel; del Pilar Santos, Rocio; De los Santos, Maxy B.; Donovan, Ngami; Ransom, Janet H.; Ramos Ttito, Ana Pilar; Llanos Cuentas, Elmer Alejandro (Public Library of Science, 2023)
    Background Cutaneous leishmaniasis (CL) is a neglected disease and a public health problem in Latin America. The diagnosis of CL in poor hyperendemic regions relies to large extent on the identification of amastigotes in ...
  • Housing Characteristics and Leishmaniasis: A Systematic Review 
    Calderón-Anyosa, Renzo; Gálvez-Petzoldt, Camila; Garcia Funegra, Patricia Jannet; Cárcamo Cavagnaro, César Paul Eugenio (American Society of Tropical Medicine and Hygiene, 2018)
    Leishmaniasis is a major neglected tropical disease associated with high rates of disability and death. This disease is associated with poverty, which can be reflected in housing quality, especially in rural areas. This ...
  • Inmunomodulación de macrófagos por dos compuestos aislados de Schkuhria pinnata, contra Leishmania infantum 
    Matos Echevarría, Daniel Ernesto (Universidad Peruana Cayetano HerediaPE, 2018)
    En la búsqueda de drogas que potencien la respuesta inmunitaria contra el parásito Leishmania, se evaluaron dos lactonas sesquiterpénicas (SKI y SKII), aisladas de la planta Schkuhria pinnata (Lam.) Kuntze. Dichos compuestos ...
  • Leishmaniasis cutánea: perfil clínico y epidemiológico de un centro de referencia nacional entre los años 2012-2022 
    Cuizano Sachun, Omar Alejandro; Guillen Huaylla, Angel Eduardo (Universidad Peruana Cayetano HerediaPE, 2024)
    Antecedentes: La leishmaniasis cutánea (LC) es una infección tropical endémica con un amplio espectro clínico. El diagnostico involucra tanto la clínica como exámenes auxiliares. Existen distintas modalidades de tratamiento. ...
  • Molecular epidemiology and diagnosis of Leishmania: What have we learnt from genome structure and function? 
    Dujardin, J.; Victoir, K.; De Doncker, S.; Guerbouj, S.; Arévalo Zelada, Jorge Luis; Le Ray, D. (Oxford University Press, 2002)
    This paper reviews our exploration of the dynamics of the Leishmania genome and its contribution to epidemiology and diagnosis. We used as a model Peruvian populations of L. (Viannia) braziliensis and L. (V.) peruviana, 2 ...
  • Neurological manifestations of human leishmaniasis 
    Llanos Cuentas, Elmer Alejandro; Valencia, Braulio M.; Petersen, Christine A. (Elsevier, 2013)
    Leishmaniasis is a spectral disease, caused by obligate intracellular protozoa of the species Leishmania. There are multiple reported instances where neurological manifestations, whether central or peripheral, are described. ...
  • New salicylamide and sulfonamide derivatives of quinoxaline 1,4-di-N-oxide with antileishmanial and antimalarial activities 
    Barea, C.; Pabón, A.; Castillo Pareja, Denis Helan; Zimic-Peralta, Mirko Juan; Quiliano, M.; Galiano, S.; Pérez-Silanes, S.; Monge, A.; Deharo, E.; Aldana, I. (Elsevier, 2011)
    Continuing with our efforts to identify new active compounds against malaria and leishmaniasis, 14 new 3-amino-1,4-di-N-oxide quinoxaline-2- carbonitrile derivatives were synthesized and evaluated for their in vitro ...
  • Peptides and methods for the detection of leishmaniasis 
    Arevalo Zelada Jorge Luis; Deharo, Eric; Privat-Maldonado, Angela (Office of the Controller General of Patents, Designs and Trade MarksIN, 2016-12-08)
    La presente invención se refiere a péptidos y métodos para la detección de anticuerpos anti-leishmania en individuos sospechosos de infección por el parásito protozoario del género Leishmania, especialmente infección por ...
  • Real-time PCR assay for detection and quantification of Leishmania (Viannia) organisms in skin and mucosal lesions: Exploratory study of parasite load and clinical parameters 
    Jara, Marlene; Adaui, Vanessa; Valencia, Braulio M.; Martinez, Dalila; Alba, Milena; Castrillon, Carlos; Cruz, Maria; Cruz, Israel; Van der Auwera, Gert; Llanos Cuentas, Elmer Alejandro; Dujardin, Jean-Claude; Arévalo Zelada, Jorge Luis (American Society for Microbiology, 2013)
    Earlier histopathology studies suggest that parasite loads may differ between cutaneous leishmaniasis (CL) and mucosal leishmaniasis (ML) lesions and between acute and chronic CL. Formal demonstration requires highly ...
  • Recombinant antigens for specific and sensitive serodiagnosis of Latin American tegumentary leishmaniasis 
    Montoya, Y.; Leon, C.; Talledo Albujar, Michael John; Nolasco, O.; Padilla, C.; Muñoz-Najar, U.; Barker, D.C. (Oxford University Press, 1997)
    The diagnostic potential of recombinant leishmanial antigens for Latin American tegumentary leishmaniasis (LATL) was examined. Two Leishmania (Viannia) peruviana recombinant proteins, T26-U2 and T26-U4, were assessed by ...
  • Tegumentary leishmaniasis and coinfections other than HIV 
    Martinez, D. Y.; Verdonck, K.; Kaye, P. M.; Adaui, Vanessa; Polman, K.; Llanos Cuentas, Elmer Alejandro; Dujardin, J.; Boelaert, M. (Public Library of Science, 2018)
    Infectious diseases are often studied one by one, but people can have more than one infection at the same time. This is likely to happen when different microorganisms are linked to specific geographical regions or living ...
  • Ultrasonographic Characteristics of Cutaneous Leishmaniasis. 
    Saavedra, A. C.; Valencia, B. M.; Tueros, P.; Wortsman, X.; Llanos Cuentas, Elmer Alejandro; Lavarello, R. J. (Wiley, 2019)
    Cutaneous leishmaniasis (CL) is an ulcerative skin parasitic disease common in people living in tropical regions and travelers(1) . Lesions characteristics (e.g., self-healing and treatment response) are extremely variable. ...
  • Volumetric monitoring of cutaneous leishmaniasis ulcers: can camera be as accurate as laser scanner? 
    Zenteno, O.; González, Eduardo; Treuillet, S.; Valencia, B. M.; Castaneda, B.; Llanos Cuentas, Elmer Alejandro; Lucas, Y. (Taylor and Francis, 2018)
    Cavity volume is an important clinical index for the assessment of the healing process and effectiveness of treatment applied on chronic ulcers. Recently, 3D scanners have proven to effectively track ulcer’s volume evolution. ...

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