Listar por tema "drug megadose"

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  • Acute and chronic elevation of erythropoietin in the brain improves exercise performance in mice without inducing erythropoiesis 
    Schuler, B.; Vogel, J.; Grenacher, B.; Jacobs, R.A.; Arras, M.; Gassmann, M. (Wiley, 2012)
    Application of recombinant human erythropoietin (rhEpo) improves exercise capacity by stimulating red blood cell production that, in turn, enhances oxygen delivery and utilization. Apart from this, when applied at high ...
  • Corticosteroid use in neurocysticercosis 
    Nash, T.E.; Mahanty, S.; García Lescano, Héctor Hugo (Taylor and Francis, 2011)
    The cystic larvae of Taenia solium commonly infect the human nervous system, resulting in neurocysticercosis, a major contributor to seizure disorders in most of the world. Inflammation around the parasites is a hallmark ...
  • Latin American algorithm for treatment of relapsing-remitting multiple sclerosis using disease-modifying agents 
    Finkelsztejn, A.; Gabbai, A.A.; Fragoso, Y.D.; Carrá, A.; Macías-Islas, M.A.; Arcega-Revilla, R.; García-Bonitto, J.; Oehninger-Gatti, C.L.; Orozco-Escobar, G.; Tarulla, A.; Vergara, F.; Vizcarra-Escobar, Darwin (SP Academia Brasileira de Neurologia, 2012)
    Objective: It is estimated that circa 50,000 individuals have relapsing-remitting multiple sclerosis in Latin America. European and NorthAmerican algorithms for the treatment of multiple sclerosis do not foresee our regional ...
  • Novel antibodies directed against the human erythropoietin receptor: Creating a basis for clinical implementation 
    Maxwell, P.; Melendez-Rodríguez, F.; Matchett, K.B.; Aragones, J.; Ben-Califa, N.; Jaekel, H.; Hengst, L.; Lindner, H.; Bernardini, A.; Brockmeier, U.; Fandrey, J.; Grunert, F.; Oster, H.S.; Mittelman, M.; El-Tanani, M.; Thiersch, M.; Schneider Gasser, E.M.; Gassmann, M.; Dangoor, D.; Cuthbert, R.J.; Irvine, A.; Jordan, A.; Lappin, T.; Thompson, J.; Neumann, D. (Wiley, 2014)
    Recombinant human erythropoietin (rHuEPO) is an effective treatment for anaemia but concerns that it causes disease progression in cancer patients by activation of EPO receptors (EPOR) in tumour tissue have been controversial ...
  • Optimizing outcomes in multiple sclerosis: Consensus guidelines for the diagnosis and treatment of multiple sclerosis in Latin America 
    Carra, A.; Macías Islas, M.A.; Gabbai, A.A.; Correale, J.; Bolana, C.; Sotelo, E.D.; Bonitto, J.G.; Vergara Edwards, F.; Vizcarra-Escobar, Darwin (SAGE Publications, 2011)
    Objective: The prevalence of multiple sclerosis (MS) in Latin America varies across different studies but an intermediate risk and increased frequency of the disease have been reported in recent years. The circumstances ...
  • Plasmodium vivax morbidity after radical cure: A cohort study in Central Vietnam 
    Pham, T.V.; Van Nguyen, H.; Aguirre, A.R.; Van Nguyen, V.; Cleves, M.A.; Nguyen, X.X.; Nguyen, T.T.; Tran, D.T.; Le, H.X.; Hens, N.; Rosanas-Urgell, A.; D’alessandro, U.; Speybroeck, N.; Erhart, A. (Public Library of Science, 2019)
    Background: In Vietnam, the importance of vivax malaria relative to falciparum during the past decade has steadily increased to 50%. This, together with the spread of multidrug-resistant Plasmodium falciparum, is a major ...

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