Publicación: In vivo wound-healing activity of oleanolic acid derived from the acid hydrolysis of Anredera diffusa
| dc.contributor.author | Moura-Letts, Gustavo | |
| dc.contributor.author | Villegas, Leon F. | |
| dc.contributor.author | Marçalo, Ana | |
| dc.contributor.author | Vaisberg, Abraham J. | |
| dc.contributor.author | Hammond, Gerald B. | |
| dc.date.accessioned | 2026-05-01T06:26:26Z | |
| dc.date.issued | 2006 | |
| dc.description.abstract | Anredera diffusa is used as a wound-healing agent in traditional Peruvian medicine. Acid hydrolysis of the bioactive ethanolic extract, followed by in vivo activity-guided fractionation, yielded oleanolic acid, with a wound-healing activity equivalent to 42.9% (p < 0.01) above the control. The highest cicatrizant activity in mice was obtained by applying 40 μg of oleanolic acid per gram of body weight. © 2006 American Chemical Society and American Society of Pharmacognosy. | en_US |
| dc.description.sponsorship | National Institute of General Medical Sciences, NIGMS, (R15GM059049); National Institute of General Medical Sciences, NIGMS | es_PE |
| dc.identifier.doi | https://doi.org/10.1021/np0601152 | |
| dc.identifier.scopus | 2-s2.0-33746580850 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12866/19463 | |
| dc.language.iso | eng | |
| dc.relation.ispartof | urn:issn:0163-3864 | |
| dc.relation.ispartofseries | Journal of Natural Products | |
| dc.relation.issn | 0163-3864 | |
| dc.rights | http://purl.org/coar/access_right/c_14cb | |
| dc.title | In vivo wound-healing activity of oleanolic acid derived from the acid hydrolysis of Anredera diffusa | en_US |
| dc.type | https://purl.org/coar/resource_type/c_2df8fbb1 | |
| dc.type.local | Artículo de revista | |
| dc.type.version | info:eu-repo/semantics/publishedVersion | |
| dspace.entity.type | Publication |