dc.contributor.author |
Nigo, Masayuki |
|
dc.contributor.author |
Cevallos, Catalina Salinas |
|
dc.contributor.author |
Woods, Krystina |
|
dc.contributor.author |
Flores, Vicente Maco |
|
dc.contributor.author |
Francis, Gweneth |
|
dc.contributor.author |
Perlman, David C. |
|
dc.contributor.author |
Revuelta, Manuel |
|
dc.contributor.author |
Mildvan, Donna |
|
dc.contributor.author |
Waldron, Mary |
|
dc.contributor.author |
Gomez, Tessa |
|
dc.contributor.author |
Koshy, Sanjana |
|
dc.contributor.author |
Jodlowski, Tomasz |
|
dc.contributor.author |
Riley, William |
|
dc.contributor.author |
Ruhe, Jorg J. |
|
dc.date.accessioned |
2022-01-04T20:29:54Z |
|
dc.date.available |
2022-01-04T20:29:54Z |
|
dc.date.issued |
2013 |
|
dc.identifier.uri |
https://hdl.handle.net/20.500.12866/10377 |
|
dc.description.abstract |
We performed a nested case-control study (ratio of 1:4) on the emergence of tigecycline-resistant multidrug-resistant Klebsiella pneumoniae (TR-MDRKP) isolates among patients who initially presented with a tigecycline-susceptible MDRKP isolate. Out of 260 patients, 24 (9%) had a subsequent clinical culture positive for a TR-MDRKP isolate within the 90-day follow-up period. On logistic regression analyses, receipt of tigecycline (adjusted odds ratio [OR], 5.06; 95% confidence interval [CI], 1.80 to 14.23; P = 0.002) was the only independent predictor of subsequent isolation of a TR strain. |
en_US |
dc.language.iso |
eng |
|
dc.publisher |
American Society for Microbiology |
|
dc.relation.ispartofseries |
Antimicrobial Agents and Chemotherapy |
|
dc.rights |
info:eu-repo/semantics/restrictedAccess |
|
dc.rights.uri |
https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es |
|
dc.subject |
human |
en_US |
dc.subject |
controlled study |
en_US |
dc.subject |
bacterium culture |
en_US |
dc.subject |
case control study |
en_US |
dc.subject |
Aged, 80 and over |
en_US |
dc.subject |
Time Factors |
en_US |
dc.subject |
bacterial strain |
en_US |
dc.subject |
Microbial Sensitivity Tests |
en_US |
dc.subject |
Anti-Bacterial Agents |
en_US |
dc.subject |
antibiotic therapy |
en_US |
dc.subject |
clinical article |
en_US |
dc.subject |
follow up |
en_US |
dc.subject |
Follow-Up Studies |
en_US |
dc.subject |
drug exposure |
en_US |
dc.subject |
Logistic Models |
en_US |
dc.subject |
drug treatment failure |
en_US |
dc.subject |
Drug Resistance, Multiple, Bacterial |
en_US |
dc.subject |
bacterium isolate |
en_US |
dc.subject |
aminoglycoside |
en_US |
dc.subject |
quinolone derivative |
en_US |
dc.subject |
monotherapy |
en_US |
dc.subject |
antibiotic resistance |
en_US |
dc.subject |
cephalosporin |
en_US |
dc.subject |
Klebsiella pneumoniae |
en_US |
dc.subject |
tigecycline |
en_US |
dc.subject |
vancomycin |
en_US |
dc.subject |
clindamycin |
en_US |
dc.subject |
urinary tract infection |
en_US |
dc.subject |
molecular typing |
en_US |
dc.subject |
aztreonam |
en_US |
dc.subject |
carbapenem |
en_US |
dc.subject |
Charlson Comorbidity Index |
en_US |
dc.subject |
Klebsiella Infections |
en_US |
dc.subject |
linezolid |
en_US |
dc.subject |
metronidazole |
en_US |
dc.subject |
Minocycline |
en_US |
dc.subject |
multidrug resistant Klebsiella pneumoniae |
en_US |
dc.subject |
polymyxin |
en_US |
dc.title |
Nested case-control study of the emergence of tigecycline resistance in multidrug-resistant Klebsiella pneumoniae |
en_US |
dc.type |
info:eu-repo/semantics/article |
|
dc.identifier.doi |
https://doi.org/10.1128/AAC.00827-13 |
|
dc.subject.ocde |
https://purl.org/pe-repo/ocde/ford#3.02.21 |
|
dc.relation.issn |
1098-6596 |
|