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Relationship between interpregnancy interval and birth defects in Washington State

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dc.contributor.author Kwon, S.
dc.contributor.author Lazo-Escalante, M.
dc.contributor.author Villaran, M.V.
dc.contributor.author Li, C.I.
dc.date.accessioned 2022-01-18T19:26:49Z
dc.date.available 2022-01-18T19:26:49Z
dc.date.issued 2012
dc.identifier.uri https://hdl.handle.net/20.500.12866/10916
dc.description.abstract Objective: Interpregnancy interval (IPI) influences numerous adverse perinatal outcomes. IPI's impact on birth defects is unclear. Study Design:We conducted a population-based case-control study, using 1998 to 2008 administrative data from Washington State. A total of 10 772 cases, women whose second of two births resulted in an infant with a birth defect, were compared with 32 310 controls, women whose second of two births did not result in an infant with a birth defect. Result: Compared with mothers with an IPI between 18 to 23 months, those with an IPI <6 months or ≥60 months had elevated risks of delivering an infant with a birth defect (odds ratio=1.15, 95% confidence interval: 1.03 to 1.28, and odds ratio=1.15, 95% confidence interval: 1.04 to 1.26, respectively). Conclusion: We observed a J-shaped relationship between IPI and risk of having an infant with a birth defect. As this is one of the first studies to evaluate this association, confirmatory studies are needed. en_US
dc.language.iso eng
dc.publisher Springer
dc.relation.ispartofseries Journal of Perinatology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Case-Control Studies en_US
dc.subject Humans en_US
dc.subject risk assessment en_US
dc.subject Risk Factors|article en_US
dc.subject controlled study en_US
dc.subject major clinical study en_US
dc.subject cardiovascular disease en_US
dc.subject central nervous system disease en_US
dc.subject gastrointestinal disease en_US
dc.subject United States en_US
dc.subject educational status en_US
dc.subject body mass en_US
dc.subject infant en_US
dc.subject Infant, Newborn en_US
dc.subject Pregnancy en_US
dc.subject Pregnancy Outcome en_US
dc.subject marriage en_US
dc.subject prenatal care en_US
dc.subject gender en_US
dc.subject maternal age en_US
dc.subject respiratory tract disease en_US
dc.subject cleft lip en_US
dc.subject cleft palate en_US
dc.subject population based case control study en_US
dc.subject birth defects en_US
dc.subject Birth Intervals en_US
dc.subject chromosome aberration en_US
dc.subject Congenital Abnormalities en_US
dc.subject ear disease en_US
dc.subject eye disease en_US
dc.subject interpregnancy interval en_US
dc.subject Kotelchuck Index en_US
dc.subject live birth en_US
dc.subject musculoskeletal disease en_US
dc.subject paternal age en_US
dc.subject perinatal outcomes en_US
dc.subject race en_US
dc.subject urogenital tract disease en_US
dc.subject Washington en_US
dc.title Relationship between interpregnancy interval and birth defects in Washington State en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1038/jp.2011.49
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.02
dc.relation.issn 1476-5543


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