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Browsing Artículos by Subject "IC 50"

Now showing items 1-7 of 7

Activity-guided isolation of antileishmanial compounds from Piper hispidum

Ruiz, C.; Haddad, M.; Alban, J.; Bourdy, G.; Reategui, R.; Castillo Pareja, Denis Helan; Sauvain, Michel Henri Auguste; Deharo, E.; Estevez, Y.; Arévalo Zelada, Jorge Luis; Rojas, R. (Elsevier, 2011)

The bioassay-guided purification of the ethanolic extract from the leaves of Piper hispidum led to the isolation of one new amide, N-2-(3′,4′, 5′-trimethoxyphenyl)ethyl-2-hydroxybenzamide (1) as well as two known chalcones ...
Antileishmanial sesquiterpene lactones from Pseudelephantopus spicatus, a traditional remedy from the Chayahuita Amerindians (Peru). Part III

Odonne, G.; Herbette, G.; Eparvier, V.; Bourdy, G.; Rojas, R.; Sauvain, Michel Henri Auguste; Stien, D. (Elsevier, 2011)

Ethnopharmacological relevance: The study of traditional remedies used by the Chayahuita, an ethnic group from the Peruvian Amazonia, has prompted us to investigate in detail the ethanolic extract of Pseudelephantopus ...
Cytotoxic and anti-infective phenolic compounds isolated from Mikania decora and Cremastosperma microcarpum

Aponte, J.C.; Jin, Z.; Vaisberg Wollach, Abraham Jaime; Castillo Pareja, Denis Helan; Málaga, E.; Lewis, W.H.; Sauvain, Michel Henri Auguste; Gilman, Robert Hugh; Hammond, G.B. (Georg Thieme Verlag, 2011)

An anticancer-bioassay guided isolation of the ethanol extract and fractions of two plants from the Peruvian rainforest, Mikania decora and Cremastosperma microcarpum, led to the characterization of one abundant diterpene, ...
Dihydrochalcones and benzoic acid derivatives from piper dennisii

Cabanillas Amado, Billy Joel; Le Lamer, A.-C.; Castillo Pareja, Denis Helan; Arévalo Zelada, Jorge Luis; Estevez, Y.; Rojas, R.; Valadeau, C.; Bourdy, G.; Sauvain, Michel Henri Auguste; Fabre, N. (Georg Thieme Verlag, 2012)

Two new dihydrochalcones, as well as eight known compounds, piperaduncin C, 2,6-dihydroxy-4-methoxydihydrochalcone, 4,2,6-trihydroxy-4-methoxydihydrochalcone, 4-hydroxy-3,5-bis(3-methyl-2- butenyl)-benzoic acid, ...
Docking and quantitative structure-activity relationship studies for 3-fluoro-4-(pyrrolo[2,1-f][1,2,4]triazin-4-yloxy)aniline, 3-fluoro-4-(1H- pyrrolo[2,3-b]pyridin-4-yloxy)aniline, and 4-(4-amino-2-fluorophenoxy)-2- pyridinylamine derivatives as c-Met kinase inhibitors

Caballero, J.; Quiliano, M.; Alzate-Morales, J.H.; Zimic-Peralta, Mirko Juan; Deharo, E. (Springer, 2011)

We have performed docking of 3-fluoro-4-(pyrrolo[2,1-f][1,2,4]triazin-4- yloxy)aniline (FPTA), 3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)aniline (FPPA), and 4-(4-amino-2-fluorophenoxy)-2-pyridinylamine (AFPP) derivatives ...
Simultaneous RNA quantification of human and retroviral genomes reveals intact interferon signaling in HTLV-1-infected CD4+ T cell lines

Moens, B.; Pannecouque, C.; Lápez, G.; Talledo Albujar, Michael John; Gotuzzo Herencia, José Eduardo; Khouri, R.; Bittencourt, A.; Farré, L.; Galvão-Castro, B.; Vandamme, A.-M.; Van Weyenbergh, J. (BioMed Central, 2012)

Background: IFN- contributes extensively to host immune response upon viral infection through antiviral, pro-apoptotic, antiproliferative and immunomodulatory activities. Although extensively documented in various types ...
Voriconazole as a first-line treatment against potentially pathogenic Acanthamoeba strains from Peru

Cabello Vílchez, Alfonso Martín; Martín-Navarro, C.M.; López-Arencibia, A.; Reyes-Batlle, M.; Sifaoui, I.; Valladares, B.; Piñero, J.E.; Lorenzo-Morales, J. (Springer Verlag, 2013)

Pathogenic strains of Acanthamoeba genus are the causative agents of fatal granulomatous amoebic encephalitis and a serious sight-threatening infection of the eye known as Acanthamoeba keratitis. In a previous study, ...

Browsing Artículos by Subject "IC 50"

Browsing Artículos by Subject "IC 50"

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