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Genome Analysis of Triploid Hybrid Leishmania Parasite from the Neotropics
Van den Broeck, F.; Heeren, S.; Maes, I.; Sanders, M.; Cotton, J.A.; Cupolillo, E.; Alvarez Torres, Eugenia Albertina; Garcia, L.; Tasia, M.; Marneffe, A.; Dujardin, J.-C.; Van der Auwera, G.
We discovered a hybrid Leishmania parasite in Costa Rica that is genetically similar to hybrids from Panama. Genome analyses demonstrated the hybrid is triploid and identified L. braziliensis and L. guyanensis-related strains as parents. Our findings highlight the existence of poorly sampled Leishmania (Viannia) variants infectious to humans.