Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021

Parekh, U.; Sanabria, J.; Krishan, K.; Boloor, A.; Mirfakhraie, R.; Ribeiro, D.; Asmelash, D.; Jayapal, S.K.; Sawhney, M.; Rezaei, N.; Bah, S.; Athar, M.; Kuttikkattu, A.; Bhaskar, S.; Rapaka, D.; Areda, D.; Barengo, N.C.; Koohestani, H.R.; Dongarwar, D.; Rwegerera, G.M.; Gebrehiwot, M.; Odukoya, O.O.; Iyasu, A.N.; Rahmani, S.; Shokri, F.; Skryabina, A.A.; Seylani, A.; Tesler, R.; Alinia, T.; Hasani, H.; Dadras, O.; Saber-Ayad, M.M.; Parekh, T.; Edinur, H.A.; Yonemoto, N.; Sahebkar, A.; Bodolica, V.; Taheri, E.; Mahmoudi, R.; Hossain, S.; Le, T.T.T.; Haddadi, R.; Gaidhane, A.M.; Deo, S.V.; Somayaji, R.; Kim, M.S.; Cao, C.; Rasali, D.P.; Chowdhury, R.; Chung, S.-C.; Amusa, G.A.; Adegboye, O.A.; Etaee, F.; Akinyemi, R.O.; Zaman, S.B.; Safi, S.Z.; Suleman, M.; Smith, A.E.; Chen, S.; Karaye, I.M.; Valizadeh, R.; Bardhan, M.; Majeed, A.; Wei, M.Y.W.; Salehi, M.A.; Coberly, K.; Armocida, B.; Khanal, S.; Mai, A.T.; Lee, P.H.; Mohamed, N.S.; Mwita, J.C.; Jayawardena, R.; Sun, J.; Choudhari, S.G.; Hosseinzadeh, M.; Kandel, H.; Bekele, A.B.; Ekholuenetale, M.; Khatatbeh, M.M.; Sabzmakan, L.; Kazemian, S.; Shaikh, M.A.; Qattea, I.; Hankey, G.J.; Mahmoud, M.A.; Shobeiri, P.; Kabthymer, R.H.; Dascalu, A.M.; Berhie, A.Y.; Qadir, M.M.F.; Rezazadeh, H.; Addo, I.Y.; Sharif-Askari, N.S.; Yada, D.Y.; Awaisu, A.; Mojiri-Forushani, H.; Bitaraf, S.; Kostev, K.; Baig, A.A.; Marateb, H.R.; Wu, Y.; Nigatu, Y.T.; Joseph, N.; Getacher, L.; Adane, T.D.; Chu, D.-T.; Kundu, S.; Legesse, S.M.; Mahjoub, S.; Ghassemi, F.; Tonelli, M.; Dutta, S.; Temsah, M.-H.; Pandi-Perumal, S.R.; Feng, X.; Sahoo, S.S.; Garcia-Gordillo, M.A.; Ghalibaf, A.M.; Columbus, A.; Gebremeskel, T.G.; Mirza-Aghazadeh-Attari, M.; Mohammadi, M.; Taheri, M.; Ismail, N.E.; Sundström, J.; Khan, A.; Moradi, Y.; Dziedzic, A.M.; Niazi, R.K.; Rahimifard, M.; Tiyuri, A.; Saleh, M.A.; Diao, N.; Taye, B.T.; Pandey, A.; Asemu, M.T.; Kuddus, M.; Huda, M.N.; Kuddus, M.A.; Owolabi, M.O.; Nguyen, H.T.H.; Dabo, B.; Shivalli, S.; Kumar, H.; Brenner, H.; Flood, D.; Okekunle, A.P.; Vollset, S.E.; Hosseinzadeh, H.; Jonas, J.B.; Hamidi, S.; Makris, K.C.; Al-Aly, Z.; Fahim, A.; Jin, Y.; Hajibeygi, R.; Roustazadeh, A.; Avila-Burgos, L.; Dewan, S.M.R.; Harandi, H.; Endeshaw, D.; Fazli, G.; Lee, S.W.; Lallukka, T.; Heidari, G.; Chandrasekar, E.K.; Montazeri, F.; Golechha, M.; Nayak, B.P.; Lee, W.-C.; Saddik, B.; Oulhaj, A.; Haubold, J.; Bilal, F.; Tabatabaeizadeh, S.-A.; Holla, R.; Tan, K.-K.; Zhang, Z.-J.; Noreen, M.; Rashedi, S.; Lo, C.-H.; Nauman, J.; Rengasamy, K.R.R.; Sarasmita, M.A.; Zastrozhin, M.S.; Kaambwa, B.; Alvis-Guzman, N.; Duncan, B.B.; Heidari, M.; Mohammadian-Hafshejani, A.; Mini, G.K.; McLaughlin, S.A.; Batra, K.; Bikbov, B.; Sepanlou, S.G.; Almustanyir, S.; Zarea, K.; Xia, J.; Hwang, B.-F.; Schuermans, A.; Rafique, I.; Chauhan, K.; Okwute, P.G.; Upadhyay, E.; Campos, L.A.; Mokdad, A.H.; Bjegovic-Mikanovic, V.; Nguyen, P.T.; Thangaraju, P.; Ningrum, D.N.A.; Babamohamadi, H.; Denova-Gutierrez, E.; Ortiz, A.; Lucchetti, G.; Mekonnen, T.; Karanth, S.D.; Najmuldeen, H.H.R.; Askari, E.; Perna, S.; Morovatdar, N.; Bagheri, N.; El-Huneidi, W.; Okonji, O.C.; Adekanmbi, V.; Haj-Mirzaian, A.; Rahnavard, N.; Mohammadi, E.; Nagaraju, S.P.; Mons, U.; Sarabi, M.M.; Criqui, M.H.; Trico, D.; Patel, J.R.; Nargus, S.; Kebede, S.A.; Cherbuin, N.; Aali, A.; Dandona, L.; Gudayu, T.W.; Le, T.T.B.; Agarwal, G.; Solikhah, S.; Wagaye, B.; Abdulah, D.M.; Murray, C.J.L.; Haile, T.G.; van Daalen, K.R.; Varthya, S.B.; Ram, P.; Nainu, F.; Rahman, M.A.; Sabour, S.; Hossain, M.S.; Iwu, C.C.D.; Ullah, S.; Rahimi, M.; Panagiotakos, D.; Jamalpoor, Z.; Meshkat, M.; Rahman, M.H.U.; Ranjha, M.M.A.Z.; Ansar, A.; Schmidt, M.I.; Andrei, C.L.; Marzo, R.R.; Mahmudul Hasan, S.M.; Mestrovic, T.; Berhe, K.; Arnlov, J.; Baradaran, H.R.; Bennett, D.A.; Delpasand, K.; Moazen, B.; Tovani-Palone, M.R.; Monasta, L.; Tat, N.Y.; Osuagwu, U.L.; Rawal, L.; Cerin, E.; Lenzi, J.; Iyamu, I.O.; Amiri, S.; Iqbal, A.; Mossialos, E.; Belete, M.A.; Pepito, V.C.F.; Farzadfar, F.; Cruz, J.A.; Ahmad, A.; Kimokoti, R.W.; Zou, Z.; Simpson, C.R.; Badiye, A.D.; Riahi, S.M.; Vos, T.; Al Hamad, H.; Joukar, F.; Hiraike, Y.; Barrow, A.; Charan, J.; Kompani, F.; Al Hasan, S.M.A.; Vo, D.C.; Wang, F.; Aljunid, S.M.; Masoudi, R.; Rodrigues, M.; Dhama, K.; Hassanipour, S.; Catala-Lopez, F.; Dandona, R.; Vaziri, S.; Bitra, V.R.; Athari, S.S.; Adnani, Q.E.S.; Bashiri, H.; Mazzaglia, G.; Gaipov, A.; Diaz, D.; Nzoputam, O.J.; Masoudi, S.; Mahmoudimanesh, M.; Ojha, V.A.; Rezaeian, M.; Malik, I.; Vart, P.; Dalton, B.E.; Islam, R.M.; Nassereldine, H.; Ansari-Moghaddam, A.; Liu, X.; Haque, S.; Mahasha, P.W.; Abdullah, A.Y.M.; Singh, S.; Cousin, E.; Bai, R.; Tripathy, J.P.; Dessie, A.M.; Petermann-Rocha, F.E.; Iso, H.; Forouhari, A.; Stafford, L.K.; Malik, A.A.; Negash, H.; Miazgowski, T.; Jeong, W.; Palladino, R.; Tufa, D.G.; Zielińska, M.; Campos-Nonato, I.R.; Sethi, Y.; Ahmed, L.A.; Yohannis, H.K.; Hannan, M.A.; Hassen, M.B.; Latief, K.; Jacob, L.; Tsegay, G.M.; Cheema, H.A.; Asghari-Jafarabadi, M.; Larijani, B.; Barone, M.T.U.; Paudel, U.; Desai, H.D.; Pourtaheri, N.; Singh, P.; Gaihre, S.; Mallhi, T.H.; Khan, M.; Perico, N.; Abbasi-Kangevari, M.; Chadwick, J.; Onwujekwe, O.E.; Remuzzi, G.; Moniruzzaman, M.; Ali, H.; Iwagami, M.; Elgendy, I.Y.; Chowdhury, E.K.; Aboagye, R.G.; Hussain, S.; Ratan, Z.A.; Khader, Y.S.; Alemi, S.; Wang, C.; Naghavi, M.; Ahmed, S.A.; dos Santos Figueiredo, F.W.; Shanawaz, M.; Debele, G.R.; Nzoputam, C.I.; Zare, I.; Lawal, B.K.; Nguyen, D.H.; Mirrakhimov, E.M.; Mulita, F.; Diress, M.; Ganesan, B.; Shafeghat, M.; Yesiltepe, M.; Naser, A.Y.; Ikeda, N.; Barone-Adesi, F.; Itumalla, R.; Rahman, M.O.; Trihandini, I.; Mohseni, A.; Defo, B.K.; Shuval, K.; Hosseini, M.-S.; Ghadirian, F.; Roever, L.; Redwan, E.M.M.; Sanmarchi, F.; Komaki, S.; Baltatu, O.C.; Shahid, S.; Khajuria, H.; Sibhat, M.M.; Postma, M.J.; Aruleba, R.T.; Odogwu, N.M.; Tabish, M.; Fagbamigbe, A.F.; Demissie, G.D.; Zoladl, M.; Joshua, C.E.; Agyemang-Duah, W.; Calina, D.; Mardi, P.; Jebai, R.; Contreras, D.; Dashti, M.; Jayaram, S.; Rahman, M.M.; Esayas, H.L.; Fadhil, I.; Safi, S.; Zhong, C.; Li, M.-C.; Stoian, A.M.P.; AlBataineh, M.T.; Ong, K.L.; Sahoo, H.; Rashidi, M.-M.; Sanjeev, R.K.; Gupta, V.K.; Ibitoye, S.E.; Michalek, I.M.; Ahmad, S.; Guan, S.-Y.; Aravkin, A.Y.; Dai, X.; Misgina, K.H.; Malta, D.C.; Padubidri, J.R.; Noubiap, J.J.; Amare, F.; Tabatabaei, S.M.; Zodpey, S.; Shabany, M.; Butt, Z.A.; Elhadi, M.; Belgaumi, U.I.; Bahadory, S.; Lorkowski, S.; Verras, G.-I.; You, Y.; Rao, C.R.; Ekundayo, T.C.; Fischer, F.; Brauer, M.; Khan, M.A.B.; Yi, S.; Anjana, R.M.; Korzh, O.; Deng, X.; Malhotra, K.; Abbasian, M.; Roshandel, G.; Ahmad, R.; Sathish, T.; Astell-Burt, T.; Harlianto, N.I.; Nguyen, V.T.; Tromans, S.J.; Lee, S.-W.; Khubchandani, J.; Kibret, B.G.; Demisse, F.W.; Alalwan, T.A.; Morze, J.; Nangia, V.; Taki, E.; Galali, Y.; Gupta, K.; Abbasi-Kangevari, Z.; Zuniga, Y.M.H.; Seidu, A.-A.; Lozano, R.; Renzaho, A.M.N.; Petcu, I.-R.; Rahimi-Movaghar, V.; Golinelli, D.; Lindstedt, P.A.; Ramazanu, S.; Soleimani, H.; Murillo-Zamora, E.; Khateri, S.; GBD 2021 Diabetes Collaborators; Karkhah, S.; Nair, T.S.; Podder, V.; Boyko, E.J.; Hadi, N.R.; Ahmad, D.; Abate, Y.H.; Tyrovolas, S.; Ghamari, S.-H.; Chattu, V.K.; Kivimaki, M.; Yang, L.; Davila-Cervantes, C.A.; Abd-Rabu, R.; Kisa, A.; Martini, S.; Khalaji, A.; Chichagi, F.; Saeed, U.; Shah, N.S.; Islam, S.M.S.; Kahe, F.; Jonasson, J.M.; Krishnamoorthy, Y.; Lim, S.S.; Musa, K.I.; Ticoalu, J.H.V.; Abidi, H.; Verma, M.V.; Liu, C.; Gebrekidan, K.G.; Mishra, M.; Mathews, E.; Sohag, A.A.M.; Gupta, V.B.; Li, Y.; Saghazadeh, A.; Bensenor, I.M.; Pourali, G.; Magliano, D.J.; Padron-Monedero, A.; Sorensen, R.J.D.; Shashamo, B.B.; Abu-Zaid, A.; Foroumadi, R.; Anyasodor, A.E.; Abebe, E.C.; Cao, Y.; Wulandari, R.D.W.I.; Patel, J.; Dervišević, E.; Kolahi, A.-A.; Huang, J.; Larsson, A.O.; Mohammadshahi, M.; Ndejjo, R.; Afolabi, R.F.; Artamonov, A.A.; Dinu, M.; Kalhor, R.; Raee, P.; Aryan, Z.; Martorell, M.; Falahi, S.; Nizam, M.A.; Lee, S.W.H.; Rahman, M.; Aghdam, Z.B.; Baghcheghi, N.; Salomon, J.A.; ElHafeez, S.A.; Tualeka, A.R.; Miranda, J. Jaime; Hagins, H.; Belo, L.; Inbaraj, L.R.; Arriagada, C.E.A.; Shiri, R.; Rana, J.; Tamuzi, J.J.L.L.; Arkew, M.; Abedi, V.; Eshetu, H.B.; Shivakumar, K.M.; Chanie, G.S.; Hayat, K.; Rancic, N.; Kothari, N.; Ahmadi, K.; Dey, S.; Natto, Z.S.; Shafie, M.; Abolhassani, H.; Badawi, A.; Duprey, J.; Nnyanzi, L.A.; Jain, R.; Gupta, R.; Abate, M.D.; Adepoju, A.V.; Basiru, A.; AL-Ahdal, T.M.A.; Sanaye, P.M.; Jayanna, K.; Temesgen, W.A.; Rashedi, V.; Elmonem, M.A.; Ahmed, A.; Halwani, R.; Kurniasari, M.D.; Rajbhandari, B.; Faris, M.E.M.; Morrison, S.D.; Ansari, G.; Sathian, B.; Chukwu, I.S.; Bayileyegn, N.S.; Koudehi, M.F.; Sadeghi, E.; Sargazi, S.; Prates, E.J.S.; Jaja, C.; Castaneda-Orjuela, C.A.; Desale, A.T.; Riaz, M.; Rawaf, S.; Westerman, R.; Lopes, G.; Wang, Y.; Mueller, U.O.; Al-Raddadi, R.M.; Soltani-Zangbar, M.S.; Ahinkorah, B.O.; Das, S.; Alcalde-Rabanal, J.E.; Darshan, B.B.; Nguyen, H.Q.; Starodubova, A.V.; Badar, M.; Yatsuya, H.; Cho, W.C.S.; Behnoush, A.H.; Vecchia, C.L.; Wang, Z.; Thankappan, K.R.; Salahi, S.; Santric-Milicevic, M.M.; Azadnajafabad, S.; Kadashetti, V.; Kumar, N.S.; Bhat, A.N.; Rohloff, P.; Damasceno, A.A.M.; Siraj, M.S.; Arulappan, J.; Jokar, M.; Elmeligy, O.A.A.; Goleij, P.; Nour, M.G.; Mostafavi, E.; Pasovic, M.; Bhatti, J.S.; Panda-Jonas, S.; Gyawali, B.; Ameyaw, E.K.; Vaithinathan, A.G.; Arumugam, A.; Ilic, I.M.; Rahmanian, V.; Guled, R.A.; Rahmawaty, S.; Desta, F.; Singh, J.A.; Tabarés-Seisdedos, R.; Lee, M.; Pardhan, S.; Waheed, Y.; Saad, A.M.A.; Moghaddam, S.S.; Atout, M.M.W.; Janakiraman, B.; Khorashadizadeh, F.; Chidambaram, S.B.; Huynh, H.-H.; Fatehizadeh, A.; Mansouri, B.; Bayih, M.T.; Jamshidi, E.; Zhou, J.; Mamun, A.A.; Isola, G.; Djalalinia, S.; Adane, D.E.; Xu, S.; Cruz-Martins, N.; Sujata, S.; Gopalani, S.V.; Kumar, R.; Sajid, M.R.; Brazo-Sayavera, J.; Ordak, M.; Cuschieri, S.; Ilic, M.D.; Sharfaei, S.; Jahrami, H.; Gautam, R.K.; Vahabi, S.M.; Mulita, A.; Zumla, A.; Kabir, A.; Arabloo, J.; Wickramasinghe, N.D.; Arifin, H.; Carvalho, M.; Batiha, A.-M.M.; Shittu, A.; Tharwat, S.; Doan, L.P.; Thapa, R.; Basu, S.; Minh, L.H.N.; Guadie, H.A.; Rahmani, M.; Hasan, S.S.; Olufadewa, I.I.; Barnighausen, T.W.; Vasankari, T.J.; De la Cruz-Gongora, V.; Guimaraes, R.A.; Jozwiak, J.J.; Rodriguez, J.A.B.; Katoto, P.D.M.C.; Khater, A.M.; Momtazmanesh, S.; Oancea, B.; Okati-Aliabad, H.; Rashid, A.M.; Ferede, T.Y.; Misganaw, A.; Kaur, N.; Koyanagi, A.; Hay, S.I.; Bintoro, B.S.; Zikarg, Y.T.; Rias, Y.A.; Schlaich, M.P.; Moradi, M.; Car, J.; Joseph, A.; Maugeri, A.; Negoi, R.I.; Reyes, L.F.; Bagherieh, S.; Zeru, N.G.; Pereira, M.; Silva, L.M.R.; Farrokhpour, H.; Lim, L.-L.; Dash, N.R.; Ajami, M.; Ahmadi, A.; Shafaghat, T.; Xu, X.; Jafarzadeh, A.; Barchitta, M.; Zamora, N.; Zarrintan, A.; Maghazachi, A.A.; Abu-Gharbieh, E.; Thomas, N.; Agudelo-Botero, M.; Sharif-Askari, F.S.; Shannawaz, M.; Hessami, K.; Saif-Ur-Rahman, K.M.; Weldemariam, A.H.; Xiao, H.; Dhimal, M.; Wassie, G.T.

Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021

Ong, K.L.; Stafford, L.K.; McLaughlin, S.A.; Boyko, E.J.; Vollset, S.E.; Smith, A.E.; Dalton, B.E.; Duprey, J.; Cruz, J.A.; Hagins, H.; Lindstedt, P.A.; Aali, A.; Abate, Y.H.; Abate, M.D.; Abbasian, M.; Abbasi-Kangevari, Z.; Abbasi-Kangevari, M.; ElHafeez, S.A.; Abd-Rabu, R.; Abdulah, D.M.; Abdullah, A.Y.M.; Abedi, V.; Abidi, H.; Aboagye, R.G.; Abolhassani, H.; Abu-Gharbieh, E.; Abu-Zaid, A.; Adane, T.D.; Adane, D.E.; Addo, I.Y.; Adegboye, O.A.; Adekanmbi, V.; Adepoju, A.V.; Adnani, Q.E.S.; Afolabi, R.F.; Agarwal, G.; Aghdam, Z.B.; Agudelo-Botero, M.; Arriagada, C.E.A.; Agyemang-Duah, W.; Ahinkorah, B.O.; Ahmad, D.; Ahmad, R.; Ahmad, S.; Ahmad, A.; Ahmadi, A.; Ahmadi, K.; Ahmed, A.; Ahmed, A.; Ahmed, L.A.; Ahmed, S.A.; Ajami, M.; Akinyemi, R.O.; Al Hamad, H.; Al Hasan, S.M.A.; AL-Ahdal, T.M.A.; Alalwan, T.A.; Al-Aly, Z.; AlBataineh, M.T.; Alcalde-Rabanal, J.E.; Alemi, S.; Ali, H.; Alinia, T.; Aljunid, S.M.; Almustanyir, S.; Al-Raddadi, R.M.; Alvis-Guzman, N.; Amare, F.; Ameyaw, E.K.; Amiri, S.; Amusa, G.A.; Andrei, C.L.; Anjana, R.M.; Ansar, A.; Ansari, G.; Ansari-Moghaddam, A.; Anyasodor, A.E.; Arabloo, J.; Aravkin, A.Y.; Areda, D.; Arifin, H.; Arkew, M.; Armocida, B.; Arnlov, J.; Artamonov, A.A.; Arulappan, J.; Aruleba, R.T.; Arumugam, A.; Aryan, Z.; Asemu, M.T.; Asghari-Jafarabadi, M.; Askari, E.; Asmelash, D.; Astell-Burt, T.; Athar, M.; Athari, S.S.; Atout, M.M.W.; Avila-Burgos, L.; Awaisu, A.; Azadnajafabad, S.; Darshan, B.B.; Babamohamadi, H.; Badar, M.; Badawi, A.; Badiye, A.D.; Baghcheghi, N.; Bagheri, N.; Bagherieh, S.; Bah, S.; Bahadory, S.; Bai, R.; Baig, A.A.; Baltatu, O.C.; Baradaran, H.R.; Barchitta, M.; Bardhan, M.; Barengo, N.C.; Barnighausen, T.W.; Barone, M.T.U.; Barone-Adesi, F.; Barrow, A.; Bashiri, H.; Basiru, A.; Basu, S.; Basu, S.; Batiha, A.-M.M.; Batra, K.; Bayih, M.T.; Bayileyegn, N.S.; Behnoush, A.H.; Bekele, A.B.; Belete, M.A.; Belgaumi, U.I.; Belo, L.; Bennett, D.A.; Bensenor, I.M.; Berhe, K.; Berhie, A.Y.; Bhaskar, S.; Bhat, A.N.; Bhatti, J.S.; Bikbov, B.; Bilal, F.; Bintoro, B.S.; Bitaraf, S.; Bitra, V.R.; Bjegovic-Mikanovic, V.; Bodolica, V.; Boloor, A.; Brauer, M.; Brazo-Sayavera, J.; Brenner, H.; Butt, Z.A.; Calina, D.; Campos, L.A.; Campos-Nonato, I.R.; Cao, Y.; Cao, C.; Car, J.; Carvalho, M.; Castaneda-Orjuela, C.A.; Catala-Lopez, F.; Cerin, E.; Chadwick, J.; Chandrasekar, E.K.; Chanie, G.S.; Charan, J.; Chattu, V.K.; Chauhan, K.; Cheema, H.A.; Abebe, E.C.; Chen, S.; Cherbuin, N.; Chichagi, F.; Chidambaram, S.B.; Cho, W.C.S.; Choudhari, S.G.; Chowdhury, R.; Chowdhury, E.K.; Chu, D.-T.; Chukwu, I.S.; Chung, S.-C.; Coberly, K.; Columbus, A.; Contreras, D.; Cousin, E.; Criqui, M.H.; Cruz-Martins, N.; Cuschieri, S.; Dabo, B.; Dadras, O.; Dai, X.; Damasceno, A.A.M.; Dandona, R.; Dandona, L.; Das, S.; Dascalu, A.M.; Dash, N.R.; Dashti, M.; Davila-Cervantes, C.A.; De la Cruz-Gongora, V.; Debele, G.R.; Delpasand, K.; Demisse, F.W.; Demissie, G.D.; Deng, X.; Denova-Gutierrez, E.; Deo, S.V.; Dervišević, E.; Desai, H.D.; Desale, A.T.; Dessie, A.M.; Desta, F.; Dewan, S.M.R.; Dey, S.; Dhama, K.; Dhimal, M.; Diao, N.; Diaz, D.; Dinu, M.; Diress, M.; Djalalinia, S.; Doan, L.P.; Dongarwar, D.; dos Santos Figueiredo, F.W.; Duncan, B.B.; Dutta, S.; Dziedzic, A.M.; Edinur, H.A.; Ekholuenetale, M.; Ekundayo, T.C.; Elgendy, I.Y.; Elhadi, M.; El-Huneidi, W.; Elmeligy, O.A.A.; Elmonem, M.A.; Endeshaw, D.; Esayas, H.L.; Eshetu, H.B.; Etaee, F.; Fadhil, I.; Fagbamigbe, A.F.; Fahim, A.; Falahi, S.; Faris, M.E.M.; Farrokhpour, H.; Farzadfar, F.; Fatehizadeh, A.; Fazli, G.; Feng, X.; Ferede, T.Y.; Fischer, F.; Flood, D.; Forouhari, A.; Foroumadi, R.; Koudehi, M.F.; Gaidhane, A.M.; Gaihre, S.; Gaipov, A.; Galali, Y.; Ganesan, B.; Garcia-Gordillo, M.A.; Gautam, R.K.; Gebrehiwot, M.; Gebrekidan, K.G.; Gebremeskel, T.G.; Getacher, L.; Ghadirian, F.; Ghamari, S.-H.; Nour, M.G.; Ghassemi, F.; Golechha, M.; Goleij, P.; Golinelli, D.; Gopalani, S.V.; Guadie, H.A.; Guan, S.-Y.; Gudayu, T.W.; Guimaraes, R.A.; Guled, R.A.; Gupta, R.; Gupta, K.; Gupta, V.B.; Gupta, V.K.; Gyawali, B.; Haddadi, R.; Hadi, N.R.; Haile, T.G.; Hajibeygi, R.; Haj-Mirzaian, A.; Halwani, R.; Hamidi, S.; Hankey, G.J.; Hannan, M.A.; Haque, S.; Harandi, H.; Harlianto, N.I.; Mahmudul Hasan, S.M.; Hasan, S.S.; Hasani, H.; Hassanipour, S.; Hassen, M.B.; Haubold, J.; Hayat, K.; Heidari, G.; Heidari, M.; Hessami, K.; Hiraike, Y.; Holla, R.; Hossain, S.; Hossain, M.S.; Hosseini, M.-S.; Hosseinzadeh, M.; Hosseinzadeh, H.; Huang, J.; Huda, M.N.; Hussain, S.; Huynh, H.-H.; Hwang, B.-F.; Ibitoye, S.E.; Ikeda, N.; Ilic, I.M.; Ilic, M.D.; Inbaraj, L.R.; Iqbal, A.; Islam, S.M.S.; Islam, R.M.; Ismail, N.E.; Iso, H.; Isola, G.; Itumalla, R.; Iwagami, M.; Iwu, C.C.D.; Iyamu, I.O.; Iyasu, A.N.; Jacob, L.; Jafarzadeh, A.; Jahrami, H.; Jain, R.; Jaja, C.; Jamalpoor, Z.; Jamshidi, E.; Janakiraman, B.; Jayanna, K.; Jayapal, S.K.; Jayaram, S.; Jayawardena, R.; Jebai, R.; Jeong, W.; Jin, Y.; Jokar, M.; Jonas, J.B.; Joseph, N.; Joseph, A.; Joshua, C.E.; Joukar, F.; Jozwiak, J.J.; 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URI: https://hdl.handle.net/20.500.12866/14635

Fecha: 2023

Resumen:

Background: Diabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimates of diabetes prevalence and burden from 1990 to 2021, the proportion of type 1 and type 2 diabetes in 2021, the proportion of the type 2 diabetes burden attributable to selected risk factors, and projections of diabetes prevalence through 2050. Methods: Estimates of diabetes prevalence and burden were computed in 204 countries and territories, across 25 age groups, for males and females separately and combined; these estimates comprised lost years of healthy life, measured in disability-adjusted life-years (DALYs; defined as the sum of years of life lost [YLLs] and years lived with disability [YLDs]). We used the Cause of Death Ensemble model (CODEm) approach to estimate deaths due to diabetes, incorporating 25 666 location-years of data from vital registration and verbal autopsy reports in separate total (including both type 1 and type 2 diabetes) and type-specific models. Other forms of diabetes, including gestational and monogenic diabetes, were not explicitly modelled. Total and type 1 diabetes prevalence was estimated by use of a Bayesian meta-regression modelling tool, DisMod-MR 2.1, to analyse 1527 location-years of data from the scientific literature, survey microdata, and insurance claims; type 2 diabetes estimates were computed by subtracting type 1 diabetes from total estimates. Mortality and prevalence estimates, along with standard life expectancy and disability weights, were used to calculate YLLs, YLDs, and DALYs. When appropriate, we extrapolated estimates to a hypothetical population with a standardised age structure to allow comparison in populations with different age structures. We used the comparative risk assessment framework to estimate the risk-attributable type 2 diabetes burden for 16 risk factors falling under risk categories including environmental and occupational factors, tobacco use, high alcohol use, high body-mass index (BMI), dietary factors, and low physical activity. Using a regression framework, we forecast type 1 and type 2 diabetes prevalence through 2050 with Socio-demographic Index (SDI) and high BMI as predictors, respectively. Findings: In 2021, there were 529 million (95% uncertainty interval [UI] 500–564) people living with diabetes worldwide, and the global age-standardised total diabetes prevalence was 6·1% (5·8–6·5). At the super-region level, the highest age-standardised rates were observed in north Africa and the Middle East (9·3% [8·7–9·9]) and, at the regional level, in Oceania (12·3% [11·5–13·0]). Nationally, Qatar had the world's highest age-specific prevalence of diabetes, at 76·1% (73·1–79·5) in individuals aged 75–79 years. Total diabetes prevalence—especially among older adults—primarily reflects type 2 diabetes, which in 2021 accounted for 96·0% (95·1–96·8) of diabetes cases and 95·4% (94·9–95·9) of diabetes DALYs worldwide. In 2021, 52·2% (25·5–71·8) of global type 2 diabetes DALYs were attributable to high BMI. The contribution of high BMI to type 2 diabetes DALYs rose by 24·3% (18·5–30·4) worldwide between 1990 and 2021. By 2050, more than 1·31 billion (1·22–1·39) people are projected to have diabetes, with expected age-standardised total diabetes prevalence rates greater than 10% in two super-regions: 16·8% (16·1–17·6) in north Africa and the Middle East and 11·3% (10·8–11·9) in Latin America and Caribbean. By 2050, 89 (43·6%) of 204 countries and territories will have an age-standardised rate greater than 10%. Interpretation: Diabetes remains a substantial public health issue. Type 2 diabetes, which makes up the bulk of diabetes cases, is largely preventable and, in some cases, potentially reversible if identified and managed early in the disease course. However, all evidence indicates that diabetes prevalence is increasing worldwide, primarily due to a rise in obesity caused by multiple factors. Preventing and controlling type 2 diabetes remains an ongoing challenge. It is essential to better understand disparities in risk factor profiles and diabetes burden across populations, to inform strategies to successfully control diabetes risk factors within the context of multiple and complex drivers.

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Krishna; Kusuma, Yadlapalli S.; Kuulasmaa, Kari; Kyobutungi, Catherine; Laamiri, Fatima Zahra; Laatikainen, Tiina; Lachat, Carl; Laid, Youcef; Lam, Tai Hing; Landrove, Orlando; Lanska, Vera; Lappas, Georg; Laugsand, Lars E.; Laxmaiah, Avula; Bao, Khanh Le Nguyen; Le, Tuyen D.; Leclercq, Catherine; Lee, Jeannette; Lee, Jeonghee; Lehtimaki, Terho; Lekhraj, Rampal; Leon-Munoz, Luz M.; Li, Yanping; Lim, Wei-Yen; Fernanda Lima-Costa, M.; Lin, Hsien-Ho; Lin, Xu; Linneberg, Allan; Lissner, Lauren; Litwin, Mieczyslaw; Liu, Jing; Lorbeer, Roberto; Lotufo, Paulo A.; Eugenio Lozano, Jose; Luksiene, Dalia; Lundqvist, Annamari; Lunet, Nuno; Lytsy, Per; Ma, Guansheng; Machi, Suka; Maggi, Stefania; Magliano, Dianna J.; Makdisse, Marcia; Malekzadeh, Reza; Malhotra, Rahul; Rao, Kodavanti Mallikharjuna; Manios, Yannis; Mann, Jim I.; Manzato, Enzo; Margozzini, Paula; Markey, Oonagh; Marques-Vidal, Pedro; Marrugat, Jaume; Martin-Prevel, Yves; Martorell, Reynaldo; Masoodi, Shariq R.; Matsha, Tandi E.; Mazur, Artur; Mbanya, Jean Claude N.; McFarlane, Shelly R.; McGarvey, Stephen T.; McKee, Martin; McLachlan, Stela; McLean, Rachael M.; McNulty, Breige A.; Yusof, Safiah Md; Mediene-Benchekor, Sounnia; Meirhaeghe, Aline; Meisinger, Christa; Mendes, Larissa L.; Menezes, Ana Maria B.; Mensink, Gert B. M.; Meshram, Indrapal I.; Metspalu, Andres; Mi, Jie; Michaelsen, Kim F.; Mikkel, Kairit; Miller, Jody C.; Francisco Miquel, Juan; Jaime Miranda, J.; Misigoj-Durakovic, Marjeta; Mohamed, Mostafa K.; Mohammad, Kazem; Mohammadifard, Noushin; Mohan, Viswanathan; Yusoff, Muhammad Fadhli Mohd; Molbo, Drude; Moller, Niels C.; Molnar, Denes; Mondo, Charles K.; Monterrubio, Eric A.; Monyeki, Kotsedi Daniel K.; Moreira, Leila B.; Morejon, Alain; Moreno, Luis A.; Morgan, Karen; Mortensen, Erik Lykke; Moschonis, George; Mossakowska, Malgorzata; Mostafa, Aya; Mota, Jorge; Motlagh, Mohammad Esmaeel; Motta, Jorge; Mu, Thet Thet; Muiesan, Maria Lorenza; Mueller-Nurasyid, Martina; Murphy, Neil; Mursu, Jaakko; Murtagh, Elaine M.; Musa, Kamarul Imran; Musil, Vera; Nagel, Gabriele; Nakamura, Harunobu; Namesna, Jana; Nang, Ei Ei K.; Nangia, Vinay B.; Nankap, Martin; Narake, Sameer; Maria Navarrete-Munoz, Eva; Nenko, Ilona; Neovius, Martin; Nervi, Flavio; Neuhauser, Hannelore K.; Nguyen, Nguyen D.; Nguyen, Quang Ngoc; Nieto-Martinez, Ramfis E.; Ning, Guang; Ninomiya, Toshiharu; Nishtar, Sania; Noale, Marianna; Norat, Teresa; Noto, Davide; Al Nsour, Mohannad; O'Reilly, Dermot; Ochoa-Aviles, Angelica M.; Oh, Kyungwon; Olayan, Iman H.; Anselmo Olinto, Maria Teresa; Oltarzewski, Maciej; Omar, Mohd A.; Onat, Altan; Ordunez, Pedro; Ortiz, Ana P.; Osler, Merete; Osmond, Clive; Ostojic, Sergej M.; Otero, Johanna A.; Overvad, Kim; Paccaud, Fred Michel; Padez, Cristina; Pajak, Andrzej; Palli, Domenico; Palloni, Alberto; Palmieri, Luigi; Panda-Jonas, Songhomitra; Panza, Francesco; Parnell, Winsome R.; Parsaeian, Mahboubeh; Pednekar, Mangesh S.; Peeters, Petra H.; Peixoto, Sergio Viana; Pereira, Alexandre C.; Perez, Cynthia M.; Peters, Annette; Peykari, Niloofar; Pham, Son Thai; Pigeot, Iris; Pikhart, Hynek; Pilav, Aida; Pilotto, Lorenza; Pistelli, Francesco; Pitakaka, Freda; Piwonska, Aleksandra; Piwonski, Jerzy; Plans-Rubio, Pedro; Poh, Bee Koon; Porta, Miquel; Portegies, Marileen L. P.; Poulimeneas, Dimitrios; Pradeepa, Rajendra; Prashant, Mathur; Price, Jacqueline F.; Puiu, Maria; Punab, Margus; Qasrawi, Radwan F.; Qorbani, Mostafa; Bao, Tran Quoc; Radic, Ivana; Radisauskas, Ricardas; Rahman, Mahmudur; Raitakari, Olli; Raj, Manu; Rao, Sudha Ramachandra; Ramachandran, Ambady; Ramke, Jacqueline; Ramos, Rafel; Rampal, Sanjay; Rasmussen, Finn; Redon, Josep; Reganit, Paul Ferdinand M.; Ribeiro, Robespierre; Riboli, Elio; Rigo, Fernando; de Wit, Tobias Floris Rinke; Ritti-Dias, Raphael M.; Rivera, Juan A.; Robinson, Sian M.; Robitaille, Cynthia; Rodriguez-Artalejo, Fernando; del Cristo Rodriguez-Perez, Maria; Rodriguez-Villamizar, Laura A.; Rojas-Martinez, Rosalba; Rojroongwasinkul, Nipa; Romaguera, Dora; Ronkainen, Kimmo; Rosengren, Annika; Rouse, Ian; Rubinstein, Adolfo; Ruehli, Frank J.; Rui, Ornelas; Sandra Ruiz-Betancourt, Blanca; Russo Horimoto, Andrea R. V.; Rutkowski, Marcin; Sabanayagam, Charumathi; Sachdev, Harshpal S.; Saidi, Olfa; Salanave, Benoit; Salazar Martinez, Eduardo; Salomaa, Veikko; Salonen, Jukka T.; Salvetti, Massimo; Sanchez-Abanto, Jose; Sandjaja; Sans, Susana; Santos, Diana A.; Santos, Osvaldo; dos Santos, Renata Nunes; Santos, Rute; Sardinha, Luis B.; Sarrafzadegan, Nizal; Saum, Kai-Uwe; Savva, Savvas C.; Scazufca, Marcia; Rosario, Angelika Schaffrath; Schargrodsky, Herman; Schienkiewitz, Anja; Schmidt, Ida Maria; Schneider, Ione J.; Schultsz, Constance; Schutte, Aletta E.; Sein, Aye Aye; Senbanjo, Idowu O.; Sepanlou, Sadaf G.; Shalnova, Svetlana A.; Shaw, Jonathan E.; Shibuya, Kenji; Shin, Youchan; Shiri, Rahman; Siantar, Rosalynn; Sibai, Abla M.; Silva, Antonio M.; Santos Silva, Diego Augusto; Simon, Mary; Simons, Judith; Simons, Leon A.; Sjostrom, Michael; Slowikowska-Hilczer, Jolanta; Slusarczyk, Przemyslaw; Smeeth, Liam; Smith, Margaret C.; Snijder, Marieke B.; So, Hung-Kwan; Sobngwi, Eugene; Soderberg, Stefan; Soekatri, Moesijanti Y. 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Background: Underweight and severe and morbid obesity are associated with highly elevated risks of adverse health outcomes. We estimated trends in mean body-mass index (BMI), which characterises its population distribution, ...
A century of trends in adult human height

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Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height ...
Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

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Vasconcelos, A.N.; Veisani, Y.; Vidale, S.; Waheed, Y.; Wei, J.; Wang, F.; Zhao, X.G.; Wang, Y.; Yu, C.; Zhang, Z.; Wang, H.; Weiss, J.; Wiangkham, T.; Wickramasinghe, N.D.; Wu, A.; Xie, Y.; Xu, G.; Yahyazadeh Jabbari, S.; Yilgwan, C.S.; Yonemoto, N.; Younis, M.Z.; Younker, T.P.; Yu, Y.; Zaidi, S.; Zhang, J.; Zhang, Y.; Zheleva, B.; Zhu, C.; GBD 2019 Diseases and Injuries Collaborators (Elsevier, 2020)

Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The ...

Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021

Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021

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