Dementia in Latin America: Paving the way toward a regional action plan

Snyder, H.M.; Sedeño, L.; Ferreira, S.T.; Bustin, J.; Nitrini, R.; Takada, L.T.; Moguilner, S.; Muniz Terrera, G.; Santacruz Escudero, J.M.; Serafim, R.B.; Teixeira, A.L.; Pio, F.J.; Lanata, S.; de Souza, L.C.; Okada de Oliveira, M.; De Lucena Ferretti Rebustini, R.E..; Dozzi Brucki, S.M.; Kochhann, R.; de Oliveira, F.F.; Tarnanas, I.; Yassuda, M.S.; Trépel, D.; Huepe, D.; Gonzalez Billault, C.; Llibre Guerra, J.; Schilling, L.P.; Chaves, M.L.F.; Smid, J.; Mbakile Mahlanza, L.; Garcia Funegra, Patricia Jannet; Piña Escudero, S.D.; Gonzalez Campo, C.; Tavares, R.M.; Hosogi, M.L.; Miller, B.; Kumfor, F.; Camargos Bicalho, M.A.; Lillo, P.; Lopez, O.L.; Mansur, L.L.; Montesinos, R.; Aprahamian, I.; de la Cruz, M.; Court, F.A.; De Paula França Resende, E.; Ibanez, A.; Comas, A.; Slachevsky, A.; Suemoto, C.K.; Cogram, P.; Yokoyama, J.; Serrano, C.; Diehl Rodriguez, R.; Grinberg, L.T.; Muñoz Nevárez, L.A.; Sosa, A.L.; Custodio, N.; Quiroz, Y.T.; Cardona, J.F.; Ramos, C.; Guerrero Barragan, A.; Ferreira Frota, N.A.; Duque Peñailillo, L.; Miotto, E.C.; Figueredo Balthazar, M.L.; Damian, A.; Mata, I.F.; Engler, H.W.; Avila-Funes, J.A.; Cano Gutierrez, C.; Santamaría-García, H.; Caramelli, P.; Soto Añari, M.; Fajersztajn, L.; Morelli, L.; Farías, G.A.; Maier, I.; Llibre, J.; Rodrigues Palmeira, A.L.; Baez, S.; Fuentes, P.; de Gobbi Porto, F.H.; Bertolucci, P.H.F.; Kosik, K.S.; Lopera, F.; Orozco, D.; De Felice, F.G.; Ramirez, J.M.; Marques Ton, A.M.; Parra, M.A.; Ferretti, C.; Kochen, S.; Barbosa, M.T.; Ferrari, R.; Piguet, O.; García, A.M.; Beber, B.C.; Possin, K.; Solis, P.C.L.; Matallana, D.; Pintado Caipa, M.; Lira, D.

dc.contributor.author	Parra, M.A.
dc.contributor.author	Baez, S.
dc.contributor.author	Sedeño, L.
dc.contributor.author	Gonzalez Campo, C.
dc.contributor.author	Santamaría-García, H.
dc.contributor.author	Aprahamian, I.
dc.contributor.author	Bertolucci, P.H.F.
dc.contributor.author	Bustin, J.
dc.contributor.author	Camargos Bicalho, M.A.
dc.contributor.author	Cano Gutierrez, C.
dc.contributor.author	Caramelli, P.
dc.contributor.author	Chaves, M.L.F.
dc.contributor.author	Cogram, P.
dc.contributor.author	Beber, B.C.
dc.contributor.author	Court, F.A.
dc.contributor.author	de Souza, L.C.
dc.contributor.author	Custodio, N.
dc.contributor.author	Damian, A.
dc.contributor.author	de la Cruz, M.
dc.contributor.author	Diehl Rodriguez, R.
dc.contributor.author	Dozzi Brucki, S.M.
dc.contributor.author	Fajersztajn, L.
dc.contributor.author	Farías, G.A.
dc.contributor.author	De Felice, F.G.
dc.contributor.author	Ferrari, R.
dc.contributor.author	de Oliveira, F.F.
dc.contributor.author	Ferreira, S.T.
dc.contributor.author	Ferretti, C.
dc.contributor.author	Figueredo Balthazar, M.L.
dc.contributor.author	Ferreira Frota, N.A.
dc.contributor.author	Fuentes, P.
dc.contributor.author	García, A.M.
dc.contributor.author	Garcia Funegra, Patricia Jannet
dc.contributor.author	de Gobbi Porto, F.H.
dc.contributor.author	Duque Peñailillo, L.
dc.contributor.author	Engler, H.W.
dc.contributor.author	Maier, I.
dc.contributor.author	Mata, I.F.
dc.contributor.author	Gonzalez Billault, C.
dc.contributor.author	Lopez, O.L.
dc.contributor.author	Morelli, L.
dc.contributor.author	Nitrini, R.
dc.contributor.author	Quiroz, Y.T.
dc.contributor.author	Guerrero Barragan, A.
dc.contributor.author	Huepe, D.
dc.contributor.author	Pio, F.J.
dc.contributor.author	Suemoto, C.K.
dc.contributor.author	Kochhann, R.
dc.contributor.author	Kochen, S.
dc.contributor.author	Kumfor, F.
dc.contributor.author	Lanata, S.
dc.contributor.author	Miller, B.
dc.contributor.author	Mansur, L.L.
dc.contributor.author	Hosogi, M.L.
dc.contributor.author	Lillo, P.
dc.contributor.author	Llibre Guerra, J.
dc.contributor.author	Lira, D.
dc.contributor.author	Lopera, F.
dc.contributor.author	Comas, A.
dc.contributor.author	Avila-Funes, J.A.
dc.contributor.author	Sosa, A.L.
dc.contributor.author	Ramos, C.
dc.contributor.author	De Paula França Resende, E.
dc.contributor.author	Snyder, H.M.
dc.contributor.author	Tarnanas, I.
dc.contributor.author	Yokoyama, J.
dc.contributor.author	Llibre, J.
dc.contributor.author	Cardona, J.F.
dc.contributor.author	Possin, K.
dc.contributor.author	Kosik, K.S.
dc.contributor.author	Montesinos, R.
dc.contributor.author	Moguilner, S.
dc.contributor.author	Solis, P.C.L.
dc.contributor.author	De Lucena Ferretti Rebustini, R.E..
dc.contributor.author	Ramirez, J.M.
dc.contributor.author	Matallana, D.
dc.contributor.author	Mbakile Mahlanza, L.
dc.contributor.author	Marques Ton, A.M.
dc.contributor.author	Tavares, R.M.
dc.contributor.author	Miotto, E.C.
dc.contributor.author	Muniz Terrera, G.
dc.contributor.author	Muñoz Nevárez, L.A.
dc.contributor.author	Orozco, D.
dc.contributor.author	Okada de Oliveira, M.
dc.contributor.author	Piguet, O.
dc.contributor.author	Pintado Caipa, M.
dc.contributor.author	Piña Escudero, S.D.
dc.contributor.author	Schilling, L.P.
dc.contributor.author	Rodrigues Palmeira, A.L.
dc.contributor.author	Yassuda, M.S.
dc.contributor.author	Santacruz Escudero, J.M.
dc.contributor.author	Serafim, R.B.
dc.contributor.author	Smid, J.
dc.contributor.author	Slachevsky, A.
dc.contributor.author	Serrano, C.
dc.contributor.author	Soto Añari, M.
dc.contributor.author	Takada, L.T.
dc.contributor.author	Grinberg, L.T.
dc.contributor.author	Teixeira, A.L.
dc.contributor.author	Barbosa, M.T.
dc.contributor.author	Trépel, D.
dc.contributor.author	Ibanez, A.
dc.date.accessioned	2021-04-13T20:50:59Z
dc.date.available	2021-04-13T20:50:59Z
dc.date.issued	2020
dc.identifier.uri	https://hdl.handle.net/20.500.12866/9139
dc.description.abstract	Across Latin American and Caribbean countries (LACs), the fight against dementia faces pressing challenges, such as heterogeneity, diversity, political instability, and socioeconomic disparities. These can be addressed more effectively in a collaborative setting that fosters open exchange of knowledge. In this work, the Latin American and Caribbean Consortium on Dementia (LAC-CD) proposes an agenda for integration to deliver a Knowledge to Action Framework (KtAF). First, we summarize evidence-based strategies (epidemiology, genetics, biomarkers, clinical trials, nonpharmacological interventions, networking, and translational research) and align them to current global strategies to translate regional knowledge into transformative actions. Then we characterize key sources of complexity (genetic isolates, admixture in populations, environmental factors, and barriers to effective interventions), map them to the above challenges, and provide the basic mosaics of knowledge toward a KtAF. Finally, we describe strategies supporting the knowledge creation stage that underpins the translational impact of KtAF.	en_US
dc.language.iso	eng
dc.publisher	Wiley
dc.relation.ispartofseries	Alzheimer's and Dementia
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	biomarkers	en_US
dc.subject	clinical trials	en_US
dc.subject	dementia	en_US
dc.subject	epidemiology	en_US
dc.subject	evidence-based recommendations	en_US
dc.subject	genetics	en_US
dc.subject	knowledge to action framework	en_US
dc.subject	Latin America	en_US
dc.subject	networking and translational research	en_US
dc.subject	nonpharmacological interventions	en_US
dc.title	Dementia in Latin America: Paving the way toward a regional action plan	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1002/alz.12202
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.02.25
dc.relation.issn	1552-5279