Acquired oral syphilis: A multicenter study of 339 patients from South America
de Andrade, Bruno Augusto Benevenuto; de Arruda, José Alcides Almeida; Gilligan, Gerardo; Piemonte, Eduardo; Panico, René; Molina Ávila, Ignacio; Pimentel Sola, Juan Martin; Carmona Lorduy, Martha Cecilia; Pupo Marrugo, Stella; Sánchez Tatis, Angélica Sofia; Werner, Laura Cecilia; Abrahão, Aline Corrêa; Agostini, Michelle; Buoro, Luisa; Israel, Mônica Simões; Freire, Nathália de Almeida; Lima, Lucas Ambrósio; Abrantes, Thamiris de Castro; Cunha, John Lennon Silva; Pérez-de-Oliveira, Maria Eduarda; Roza, Ana Luiza Oliveira Corrêa; Vargas, Pablo Agustin; Lopes, Marcio Ajudarte; Santos-Silva, Alan Roger; de Almeida, Oslei Paes; Pontes, Flávia Sirotheau Corrêa; Pontes, Hélder Antônio Rebelo; Rondanelli, Benjamin Martínez; Villarroel-Dorrego, Mariana; Bologna-Molina, Ronell; Derderian, Nathalie; Sánchez-Romero, Celeste; Abreu, Lucas Guimarães; Fonseca, Felipe Paiva; Mesquita, Ricardo Alves; Gomez, Ricardo Santiago; Martínez-Flores, René; Delgado-Azañero, Wilson; Alves, Adriana Terezinha Neves Novellino; Lourenço, Simone de Queiroz Chaves; Coimbra, Carolina; Polignano, Giovanni Augusto Castanheira; Assunção Júnior, José Narciso Rosa; Souto, Giovanna Ribeiro; Souza, Paulo Eduardo Alencar; Horta, Martinho Campolina Rebello; González-Arriagada, Wilfredo Alejandro; Romañach, Mário José
Date:
2021
Abstract:
OBJECTIVE: To report the clinicopathologic features of acquired oral syphilis cases in South American countries. MATERIALS AND METHODS: Clinical data were retrospectively collected from the records of 18 oral diagnostic services in Argentina, Brazil, Chile, Colombia, Venezuela, Uruguay, and Peru. Serologies of nontreponemal and treponemal tests were used for diagnosis. RESULTS: The series comprised 339 cases of acquired oral syphilis. Secondary syphilis ranked as the most common stage (86.7%). Lesions were more frequent among males (58.0%) and young adults with a mean age of 33.3 years. Individuals aged 20-29 years were most affected (35.3%). The most commonly involved sites were the tongue (31.6%), lip/labial commissure (25.1%), and hard/soft palate (20.4%). Clinically, acquired oral syphilis usually presented as mucous patches (28.4%), papules (25.7%), and ulcers (18.1%). Skin manifestations occurred in 67.7% of individuals, while lymphadenopathy and fever were observed in 61.3% and 11.6% of all subjects, respectively. Most patients were treated with the benzathine penicillin G antibiotic. CONCLUSION: This report validates the spread of acquired oral syphilis infection among young adults in South America. Our directives include accessible diagnostic tools for proper disease screening, surveillance, and counselling of affected individuals, especially in low- and middle-income countries
Show full item record
Except where otherwise noted, this item's license is described as info:eu-repo/semantics/restrictedAccess
