Universidad Peruana Cayetano Heredia

Acquired oral syphilis: A multicenter study of 339 patients from South America

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dc.contributor.author de Andrade, Bruno Augusto Benevenuto
dc.contributor.author de Arruda, José Alcides Almeida
dc.contributor.author Gilligan, Gerardo
dc.contributor.author Piemonte, Eduardo
dc.contributor.author Panico, René
dc.contributor.author Molina Ávila, Ignacio
dc.contributor.author Pimentel Sola, Juan Martin
dc.contributor.author Carmona Lorduy, Martha Cecilia
dc.contributor.author Pupo Marrugo, Stella
dc.contributor.author Sánchez Tatis, Angélica Sofia
dc.contributor.author Werner, Laura Cecilia
dc.contributor.author Abrahão, Aline Corrêa
dc.contributor.author Agostini, Michelle
dc.contributor.author Buoro, Luisa
dc.contributor.author Israel, Mônica Simões
dc.contributor.author Freire, Nathália de Almeida
dc.contributor.author Lima, Lucas Ambrósio
dc.contributor.author Abrantes, Thamiris de Castro
dc.contributor.author Cunha, John Lennon Silva
dc.contributor.author Pérez-de-Oliveira, Maria Eduarda
dc.contributor.author Roza, Ana Luiza Oliveira Corrêa
dc.contributor.author Vargas, Pablo Agustin
dc.contributor.author Lopes, Marcio Ajudarte
dc.contributor.author Santos-Silva, Alan Roger
dc.contributor.author de Almeida, Oslei Paes
dc.contributor.author Pontes, Flávia Sirotheau Corrêa
dc.contributor.author Pontes, Hélder Antônio Rebelo
dc.contributor.author Rondanelli, Benjamin Martínez
dc.contributor.author Villarroel-Dorrego, Mariana
dc.contributor.author Bologna-Molina, Ronell
dc.contributor.author Derderian, Nathalie
dc.contributor.author Sánchez-Romero, Celeste
dc.contributor.author Abreu, Lucas Guimarães
dc.contributor.author Fonseca, Felipe Paiva
dc.contributor.author Mesquita, Ricardo Alves
dc.contributor.author Gomez, Ricardo Santiago
dc.contributor.author Martínez-Flores, René
dc.contributor.author Delgado-Azañero, Wilson
dc.contributor.author Alves, Adriana Terezinha Neves Novellino
dc.contributor.author Lourenço, Simone de Queiroz Chaves
dc.contributor.author Coimbra, Carolina
dc.contributor.author Polignano, Giovanni Augusto Castanheira
dc.contributor.author Assunção Júnior, José Narciso Rosa
dc.contributor.author Souto, Giovanna Ribeiro
dc.contributor.author Souza, Paulo Eduardo Alencar
dc.contributor.author Horta, Martinho Campolina Rebello
dc.contributor.author González-Arriagada, Wilfredo Alejandro
dc.contributor.author Romañach, Mário José
dc.date.accessioned 2021-10-04T23:00:55Z
dc.date.available 2021-10-04T23:00:55Z
dc.date.issued 2021
dc.identifier.uri https://hdl.handle.net/20.500.12866/9774
dc.description.abstract OBJECTIVE: To report the clinicopathologic features of acquired oral syphilis cases in South American countries. MATERIALS AND METHODS: Clinical data were retrospectively collected from the records of 18 oral diagnostic services in Argentina, Brazil, Chile, Colombia, Venezuela, Uruguay, and Peru. Serologies of nontreponemal and treponemal tests were used for diagnosis. RESULTS: The series comprised 339 cases of acquired oral syphilis. Secondary syphilis ranked as the most common stage (86.7%). Lesions were more frequent among males (58.0%) and young adults with a mean age of 33.3 years. Individuals aged 20-29 years were most affected (35.3%). The most commonly involved sites were the tongue (31.6%), lip/labial commissure (25.1%), and hard/soft palate (20.4%). Clinically, acquired oral syphilis usually presented as mucous patches (28.4%), papules (25.7%), and ulcers (18.1%). Skin manifestations occurred in 67.7% of individuals, while lymphadenopathy and fever were observed in 61.3% and 11.6% of all subjects, respectively. Most patients were treated with the benzathine penicillin G antibiotic. CONCLUSION: This report validates the spread of acquired oral syphilis infection among young adults in South America. Our directives include accessible diagnostic tools for proper disease screening, surveillance, and counselling of affected individuals, especially in low- and middle-income countries en_US
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartofseries Oral Diseases
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject public health en_US
dc.subject syphilis en_US
dc.subject Treponema pallidum en_US
dc.subject acquired syphilis en_US
dc.subject oral mucosa en_US
dc.subject sexually transmitted infections en_US
dc.title Acquired oral syphilis: A multicenter study of 339 patients from South America en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1111/odi.13963
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.14
dc.relation.issn 1601-0825


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