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Treponema pallidum pallidum Genotypes and Macrolide Resistance Status in Syphilitic Lesions among Patients at 2 Sexually Transmitted Infection Clinics in Lima, Peru

Treponema pallidum pallidum Genotypes and Macrolide Resistance Status in Syphilitic Lesions among Patients at 2 Sexually Transmitted Infection Clinics in Lima, Peru

Flores, Juan-Antonio; Vargas Rivera, Silver Keith; León Sandoval, Segundo Ramos; Perez, Danny-Giancarlo; Ramos, Lourdes-Beatriz; Chow, Jeremy; Konda, Kelika-Anne; Calvo, Gino-Mauricio; Salvatierra, Hector-J.; Klausner, Jeffrey-D.; Caceres Palacios, Carlos Fernando
URI: https://hdl.handle.net/20.500.12866/5209
Date: 2016

Abstract:

We report the circulating genotypes and the frequency of macrolide-resistance patterns among Treponema pallidum pallidum DNA isolated from syphilitic lesions from patients who attended 2 sexual health clinics in Lima, Peru. We implemented and used a molecular typing scheme to describe local T. pallidum pallidum strains. Among 14 specimens, subtype 14d/f was the most prevalent strain in 7 fully typed T. pallidum DNA specimens obtained from men who have sex with men and transgender women presenting with chancre-like lesions. No macrolide-resistance mutations were found in T. pallidum DNA from 10 lesions.

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